Mechanisms of Cell-Mediated Cytotoxicity

  • William R. Clark
  • Pierre Golstein

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 146)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Lysis by Cytotoxic T Lymphocytes: Morphological and Physiological Aspects

    1. Front Matter
      Pages 1-2
    2. Matthew F. Mescher, Steven P. Balk, Steven J. Burakoff, Steven H. Herrmann
      Pages 41-55
    3. Katherine A. Wall, Frank W. Fitch
      Pages 101-109
    4. Eric Martz, Wendy L. Parker, Maurice K. Gately, Constantine D. Tsoukas
      Pages 121-147
  3. Lysis by Non-T Cells and by Complement

    1. Front Matter
      Pages 191-192
    2. Complement

    3. ADCC

      1. Maryanna P. Henkart, Pierre A. Henkart
        Pages 227-247
      2. Peter Perlmann
        Pages 249-253
      3. Stephan Ladisch, Lisa Ulsh, Stephen A. Feig
        Pages 255-264
    4. MØCC

      1. M. E. Key, L. Hoyer, C. Bucana, M. G. Hanna Jr.
        Pages 265-314
      2. John B. Hibbs Jr., Donald L. Granger, James L. Cook, Andrew M. Lewis Jr.
        Pages 315-335
    5. NKCC

      1. Christopher S. Henney
        Pages 353-356
      2. Rolf Kiessling, Alvar Grönberg
        Pages 367-377
      3. Benjamin Bonavida, Susan C. Wright
        Pages 379-388
      4. Ronald H. Goldfarb, Tuomo Timonen, Ronald B. Herberman
        Pages 403-423
  4. The use of Antisera, Monoclonal Antibodies, and Cloned Effector Cells in the Study of Cell-Mediated Cytolysis

    1. Front Matter
      Pages 425-426
    2. Eric Martz, Denise Davignon, Konrad Kürzinger, Timothy A. Springer
      Pages 447-468
    3. Pierre Golstein, Michel Pierres, Anne-Marie Schmitt-Verhulst, Marie-Francoise Luciani, Michel Buferne, Zelig Eshhar et al.
      Pages 487-503
    4. Anne Pierres, Anne-Marie Schmitt-Verhulst, Christian Devaux, Pierre Golstein, Daniel Birnbaum, Christo Goridis et al.
      Pages 505-519
    5. Anne-Marie Schmitt-Verhulst, Pierre Golstein, Michel Buferne, Michel Pierres
      Pages 521-532
    6. David W. Lancki, Marc I. Lorber, Michael R. Loken, Frank W. Fitch
      Pages 557-562
  5. Back Matter
    Pages 589-597

About this book


The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga­ tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.


T cell antibody antigen cells cytotoxicity genetics growth factor hand lymphocytes research thinking toxicity

Editors and affiliations

  • William R. Clark
    • 1
  • Pierre Golstein
    • 2
  1. 1.University of CaliforniaLos AngelesUSA
  2. 2.Centre d’lmmunologieINSERM-CNRS de Marseille-LuminyMarseilleFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1982
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-8961-3
  • Online ISBN 978-1-4684-8959-0
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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