Cholinergic Mechanisms

Phylogenetic Aspects, Central and Peripheral Synapses, and Clinical Significance

  • Giancarlo Pepeu
  • Herbert Ladinsky

Part of the Advances in Behavioral Biology book series (ABBI, volume 25)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Develpomental and Phylogenetic Aspects of the Cholinergic Neurone

  3. Peripheral Cholinergic Synapses: Gangia

    1. N. J. Dun, A. G. Karczmar
      Pages 109-118
    2. V. Perri, O. Belluzzi, C. Biondi, P. G. Borasio, A. Capuzzo, M. E. Ferretti et al.
      Pages 119-125
    3. E. Costa, A. Guidotti, I. Hanbauer, T. Hexum, L. Saiani, H.-Y. T. Yang
      Pages 143-153
  4. Peripheral Cholinergic Synapses: Heart, Myenteric Plexus and Neuromuscular Function

  5. Peripheral Cholinergic Synapses: Presynaptic Mechanisms

  6. Peripheral Cholinergic Synapse: Postsynaptic Aspects

    1. W. H. Hopff, A. A. Hofmann, G. Riggio, P. G. Waser
      Pages 323-332
    2. A. K. Lefvert, S. Cuenoud, B. W. Fulpius
      Pages 333-341
    3. D. A. Kharkevich, A. P. Skoldinov, D. N. Samoilov, V. A. Shorr
      Pages 351-365
  7. Peripheral Cholinergic Synapse: Axonal Aspects

    1. H. C. Mautner, J. E. Jumblatt, J. K. Marquis
      Pages 367-376
    2. B. Droz, M. Brunetti, L. di Giamberardino, H. L. Koenig, G. Porcellati
      Pages 377-386
  8. Central Cholinergic Synapse: Precursors for Acetylcholine Synthesis

  9. Central Cholinergic Synapse: Synaptosomes and Brain Slices

About this book


Every three years early Spring witnesses the convening of a small group of neuroscientists from many parts of the world. They are devoted to the study of acetylcholine, the oldest of the known neurotransmitters. To assess the level of knowledge, to take stock of the still unsolved problems, to evaluate the practical meaning of their findings, the cholinologists first met in 1969 in the eerie atmosphere of a snow-covered Swedish forest, the second in the Swiss Alps, the third facing the surf and foam of the Paci­ fic waves. Finally in March 1980 Florence, her trees burgeoning in the mild rain of March, confronted them with the temptation of her monuments and museums. But the cholinologists bravely dismis­ sed the temptations and went on with the presentations and discus­ sions of the many papers which form the present book. The papers describe the most recent development of investiga­ tions on acetylcholine. They open with an extensive coverage of the developmental and phylogenetic aspects of the cholinergic neurons. The regulation of acetylcholine synthesis, release, post­ synaptic, electrical and trophic effects in the peripheral chol­ inergic synapses including ganglia, neuromuscular junction, myen­ theric plexus and heart is then covered. Special emphasis is given to the cholinergic mechanisms in the eye.


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Editors and affiliations

  • Giancarlo Pepeu
    • 1
  • Herbert Ladinsky
    • 2
  1. 1.Institute of PharmacologyUniversity of FlorenceFlorenceItaly
  2. 2.Mario Negri Institute for Pharmacological ResearchMilanItaly

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1981
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-8645-2
  • Online ISBN 978-1-4684-8643-8
  • Series Print ISSN 0099-6246
  • Buy this book on publisher's site