Purine Metabolism in Man—III

Biochemical, Immunological, and Cancer Research

  • Aurelio Rapado
  • R. W. E. Watts
  • Chris H. M. M. De Bruyn

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 122B)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Purine Metabolism Pathways and Regulation

    1. De Novo Synthesis: Precursors and Regulation

      1. R. B. Gordon, L. Thompson, L. A. Johnson, B. T. Emmerson
        Pages 1-6
      2. Donald J. Nelson, Stephen W. LaFon, Gertrude B. Elion, J. Joseph Marr, Randolph L. Berens
        Pages 7-12
      3. E. R. Tully, T. G. Sheehan
        Pages 13-17
      4. S. Nees, A. L. Gerbes, B. Willershausen-Zönnchen, E. Gerlach
        Pages 25-30
      5. Kari O. Raivio, Cheri Lazar, Henry Krumholz, Michael A. Becker
        Pages 31-34
    2. Nucleotide Metabolism

      1. Catherine M. Andres, Thomas D. Palella, Irving H. Fox
        Pages 41-43
      2. H.-G. Zimmer, H. Ibel, G. Steinkopff, H. Koschine
        Pages 45-50
    3. Salvage Pathways

      1. Thomas A. Krenitsky, George W. Koszalka, Joel V. Tuttle, David L. Adamczyk, Gertrude B. Elion, J. Joseph Marr
        Pages 51-56
      2. Roy A. Levine, Milton W. Taylor
        Pages 57-60
    4. Catabolism

      1. M. P. Rivera, M. R. Grau, J. Rigau, A. Goday
        Pages 61-67
      2. Costantino Salerno, Alessandro Giacomello
        Pages 69-72
      3. M. Kraupp, P. Chiba, M. M. Müller
        Pages 73-78
      4. Milton W. Taylor, Kailash C. Gupta, Ludmila Zawistowich
        Pages 79-84
      5. Georges Van den Berghe, Françoise Bontemps, Henri-Géry Hers
        Pages 85-86
  3. Enzymology and Purine Metabolism

    1. Phosphoribosyltransferases

    2. Nucleoside Phosphoribosylating Enzymes

      1. Joseph A. Holden, Gary S. Meredith, William N. Kelley
        Pages 123-129
      2. B. Jochimsen, B. Garber, J. S. Gots
        Pages 131-136
    3. Nucleoside Cleaving Enzymes

    4. Deaminating Enzymes

      1. Peter E. Daddona, Michael A. Frohman, William N. Kelley
        Pages 157-162
      2. Paul P. Trotta, M. Earl Balis
        Pages 163-168
      3. Nobuaki Ogasawara, Haruko Goto, Yasukazu Yamada
        Pages 169-175
      4. Peter E. Daddona, William N. Kelley
        Pages 177-181
      5. Rudolf Kuzmits, Heinrich Stemberger, Mathias M. Müller
        Pages 183-188
    5. Oxidating Enzymes

      1. A. Di Stefano, M. Pizzichini, E. Marinello
        Pages 189-196
      2. C. Auscher, N. Amory, P. van der Kemp, F. Delbarre
        Pages 197-201
  4. Pyrimidine Metabolism

  5. Lymphocyte Purine Metabolism Research

    1. Robert L. Wortmann, Beverly S. Mitchell, N. Lawrence Edwards, Irving H. Fox
      Pages 243-250
    2. Allen D. Meisel, Chandrasek Natarajan, Gary Sterba, Herbert S. Diamond
      Pages 251-257
    3. James M. Wilson, Beverly S. Mitchell, William N. Kelley
      Pages 265-270
    4. Thomas P. Zimmerman, Gerald Wolberg, Gail S. Duncan, Robert D. Deeprose, Robert J. Harvey
      Pages 271-276
    5. S. S. Matsumoto, K. O. Raivio, R. C. Willis, J. E. Seegmiller
      Pages 277-282
    6. J. P. R. M. van Laarhoven, G. Th. Spierenburg, C. H. M. M. de Bruyn, E. D. A. M. Schretlen
      Pages 283-288

About this book


These volumes contain the papers which were presented at the Third International Symposium on Purine Metabolism in Man held in Madrid (Spain) in June, 1979. The previous meetings in the series were held in Tel Aviv (Israel) and in Baden (Austria) in 1973 and 1976, respectively. The proceedings were also published by Plenum. Knowledge of the pathophysiology of the purines has developed greatly since the 1950's when it was mainly related to clinical gout, and it is now relevant to many fields of Medicine and Biology. These volumes include papers reporting new work on clinical gout and urolithiasis as well as on some of the subjects which have featured prominently in the previous volumes, including: regulatory aspects of the intermediary metabolism of purines and related com­ pounds, enzymology, methodology, and the results of mutations which affect purine metabolism. However, there have been many new develop­ ments during the last three years and the scope of the communications reflects not only increasing depth of knowledge, but also a widening of the field. This publication has clinical and fundamental impli­ cations for internal medicine, pediatrics, urology, biochemistry, immunology, genetics, and oncology.


Purine biochemistry biology metabolism mutation

Editors and affiliations

  • Aurelio Rapado
    • 1
  • R. W. E. Watts
    • 2
  • Chris H. M. M. De Bruyn
    • 3
  1. 1.Fundación Jiménez DíazMadridSpain
  2. 2.M.R.C. Clinical Research CentreHarrowEngland
  3. 3.Department of Human GeneticsUniversity of Nijmegen Faculty of MedicineNijmegenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1980
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-8561-5
  • Online ISBN 978-1-4684-8559-2
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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