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The Thrombotic Process in Atherogenesis

  • A. Bleakley Chandler
  • Karl Eurenius
  • Gardner C. McMillan
  • Curtis B. Nelson
  • Colin J. Schwartz
  • Stanford Wessler

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 104)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Conceptual Aspects

    1. Front Matter
      Pages 1-1
    2. Colin J. Schwartz, A. Bleakley Chandler, Ross G. Gerrity, Herbert K. Naito
      Pages 111-126
    3. J. F. Mustard, M. A. Packham, R. Kinlough-Rathbone
      Pages 127-144
    4. Neville Woolf
      Pages 145-167
    5. Guido Majno, Isabelle Joris
      Pages 169-225
    6. Isabelle Joris, Guido Majno
      Pages 227-233
    7. Back Matter
      Pages 235-243
  3. Interaction of Platelets and Coagulation with the Arterial Wall

    1. Front Matter
      Pages 245-245
    2. R. L. Nachman, E. A. Jaffe, B. B. Weksler, F. A. Pitlick, M. A. Gimbrone Jr., C. R. Minick
      Pages 247-252
    3. A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 253-256
    4. W. A. Thomas, J. F. Mustard, S. Moore, M. J. Karnovsky, T. P. Bersot, H. Wolinsky
      Pages 257-265
    5. A. Bleakley Chandler, Karl Eurenius, Gardner C. McMillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 267-269
  4. Risk Factors for Atherosclerosis and Thrombosis

    1. Front Matter
      Pages 271-271
    2. Henry C. McGill Jr.
      Pages 273-280
    3. Robert S. Lees, Angelina C. A. Carvalho
      Pages 301-308
    4. James M. Iacono, Rita M. Dougherty, Rodolfo Paoletti, Claudio Galli, Angelina C. A. Carvalho, Anna Ferro-Luzzi et al.
      Pages 309-327
    5. Back Matter
      Pages 329-333
  5. Lipid-Membrane Interactions of Platelets, Coagulation and the Arterial Wall at the Molecular Level

    1. Front Matter
      Pages 335-335
    2. A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 341-342
    3. A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 349-349
  6. The Thrombotic Process and Atherogenesis in Specific Arterial Injury

    1. Front Matter
      Pages 351-351
    2. Donald L. Fry
      Pages 353-356
    3. A. Bleakley Chandler, Karl Eurenius, Gardner C. McMillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 357-369
    4. Carl G. Becker
      Pages 371-378
    5. A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 379-382
  7. Animal Models of Atherosclerosis Involving the Thrombotic Process

    1. Front Matter
      Pages 383-383
    2. A. Bleakley Chandler, Karl Eurenius, Gardner C. Mcmillan, Curtis B. Nelson, Colin J. Schwartz, Stanford Wessler
      Pages 401-407
    3. Stanford Wessler
      Pages 409-417
  8. Clinical Assessment of the Thrombotic Process in Relation to Atherosclerosis

    1. Front Matter
      Pages 419-419
    2. Robert D. Rosenberg, Herbert Lau, David Beeler, Judith S. Rosenberg
      Pages 449-457
    3. Back Matter
      Pages 473-475
  9. Back Matter
    Pages 479-546

About this book

Introduction

Two infonnal meetings of consultants expert in hemostatic phenomena and in atherogenesis were held in Bethesda, Maryland, in December 1975 and February 1976 by the National Heart, Lung, and Blood Institute. Their purpose was to discuss the current status of knowledge concerning the thrombotic process in the pathogenesis of atherosclerosis. It was readily agreed that thrombosis often played a major role in plaque building and in plaque complication. It was also commented, however, that the data were qualitative in nature and that quantitative infonnation was remarkably sparse. The term thromboatherogenesis was thought to be appropriate for those phenomena in which the full expression of the thrombotic process is manifest. At the same time, recent research was noted in which what appears to be an important pathway for the initiation of atherogenesis arises from the reaction of platelets with injured arterial endothelium and'Subendothelium without necessarily involving the complete classical thrombotic process. A name was not coined for this circumstance, but it was held that thromboatherogenesis was not a fully appropriate one.

Keywords

atherosclerosis blood heart platelet thrombosis

Editors and affiliations

  • A. Bleakley Chandler
    • 1
  • Karl Eurenius
    • 2
  • Gardner C. McMillan
    • 2
  • Curtis B. Nelson
    • 3
  • Colin J. Schwartz
    • 4
  • Stanford Wessler
    • 5
  1. 1.Department of PathologyMedical College of GeorgiaUSA
  2. 2.National Heart, Lung, and Blood InstituteNational Institutes of HealthUSA
  3. 3.Division of Scientific AffairsAmerican Heart AssociationUSA
  4. 4.Department of PathologyUniversity of Texas, San AntonioUSA
  5. 5.Department of MedicineNew York University School of MedicineUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-7787-0
  • Copyright Information Springer-Verlag US 1978
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-7789-4
  • Online ISBN 978-1-4684-7787-0
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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