Boundaries between Promotion and Progression during Carcinogenesis

  • Oscar Sudilovsky
  • Henry C. Pitot
  • Lance A. Liotta

Part of the Basic Life Sciences book series (BLSC, volume 57)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction: Is There a Boundary between Promotion and Progression?

  3. The Boundaries between Promotion and Progression in Different Tissues

  4. Development and Boundaries between Promotion and Progression

    1. G. Barry Pierce, Ralph E. Parchment
      Pages 71-81
    2. Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta
      Pages 101-101
  5. Colloquium: Transgenic Mice and the Boundaries between Promotion and Progression

    1. Barbara B. Knowles, Susan Faas, Antonio Juretic, Niles Fox, Roseanne Crooke, Douglas Hanahan et al.
      Pages 111-125
  6. Oncogenes, Suppressor Genes and the Boundaries between Promotion and Progression

    1. G. Tim Bowden, Lawrence E. Ostrowski, Keith Bonham, Peter Krieg
      Pages 127-141
    2. Robert Callahan
      Pages 143-156
    3. Jeff A. Boyd, J. Carl Barrett
      Pages 183-196
    4. Peter H. Duesberg, David Goodrich, Ren-Ping Zhou
      Pages 197-211
    5. Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta
      Pages 213-219
  7. Genetic Instability and the Boundaries between Promotion and Progression

    1. Peter C. Nowell
      Pages 221-231
    2. Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta
      Pages 241-241
  8. Colloquium: At Which Point in Time Does Genetic Instability Occur in the Natural History of Cancer?

    1. Joan R. Shapiro, Bipin M. Mehta, Salah A. D. Ebrahim, Adrienne C. Scheck, Paul L. Moots, Martin R. Fiola
      Pages 243-262
    2. Oscar Sudilovsky, Lucila I. Hinrichsen, Tom K. Hei, Cecilia M. Whitacre, Jian H. Wang, Sriram Kasturi et al.
      Pages 263-277
    3. J. W. Grisham, M.-S. Tsao, L. W. Lee, G. J. Smith
      Pages 279-300
  9. The Boundaries between Promotion and Progression in Humans

    1. Istvan Valyi-Nagy, Ulrich Rodeck, Roland Kath, Maria Laura Mancianti, Wallace H. Clark, Meenhard Herlyn
      Pages 315-328
    2. Helene S. Smith, Robert Stern, Edison Liu, Chris Benz
      Pages 329-340
    3. G. H. Yoakum, L. Malan-Shibley, C. C. Harris
      Pages 341-354
    4. Patricia S. Steeg, Generoso Bevilacqua, Mark E. Sobel, Lance A. Liotta
      Pages 355-361
  10. Back Matter
    Pages 363-372

About this book


The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi­ ble changes tha. t position them in the stage of progression? Or are these two stages the same thing, but called by different names? To explore such concepts we assembled investigators with various back­ grounds and asked them to specifically address these and other questions about "The Boundaries", within the context of the session to which they con­ tributed. The conference lasted two and a half days, from Wednesday to Friday. There were at least four speakers per session with morning and after­ noon sessions each day, except on Friday when the meeting ended at noon. The first day, each speaker had 25 minutes to present a position, followed by five minutes of discussion. At the end of the session there were 40 or 50 minutes of exchange on all the issues examined. For the remaining days, there were 25 minutes of presentation and 15 minutes of discussion.


carcinogenesis carcinoma development gene expression system tissue tumor tumor progression

Editors and affiliations

  • Oscar Sudilovsky
    • 1
  • Henry C. Pitot
    • 2
  • Lance A. Liotta
    • 3
  1. 1.Case Western Reserve UniversityClevelandUSA
  2. 2.McArdle Laboratory for Cancer ResearchMadisonUSA
  3. 3.National Institutes of HealthBethesdaUSA

Bibliographic information

Industry Sectors
Health & Hospitals