Molecular Pathogenesis of Gastrointestinal Infections

  • T. Wadström
  • P. H. Mäkelä
  • A.-M. Svennerholm
  • H. Wolf-Watz

Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 58)

Table of contents

  1. Front Matter
    Pages i-x
  2. The Mucosal Surface

    1. Robert W. Lobley
      Pages 1-8
    2. Karl-Anders Karlsson, Jonas Ångström, Susann Teneberg
      Pages 9-21
    3. Ingemar Carlstedt, Stefan Elmquist, Ingela Ljusegren, Gunnar C. Hansson
      Pages 23-28
    4. Paul S. Cohen, Beth A. McCormick, David P. Franklin, Robert L. Burghoff, David C. Laux
      Pages 29-31
    5. Tore Midtvedt, Göran Larson, Catharina Svanborg
      Pages 33-36
  3. The Parasite

    1. Bernt Eric Uhlin, Björn Dagberg, Kristina Forsman, Mikael Göransson, Birgit Knepper, Peter Nilsson et al.
      Pages 55-58
    2. Wim Gaastra, Anja M. Hamers, Bart J. A. M. Jordi, Paul H. M. Savelkoul, Geraldine A. Willshaw, Moyra M. McConnell et al.
      Pages 61-70
    3. Heinz Hoschützky, Thomas Bühler, Ralph Ahrens, Klaus Jann
      Pages 71-78
    4. Per Klemm, Karen A. Krogfelt
      Pages 87-92
    5. Inga Benz, M. Alexander Schmidt
      Pages 103-105
  4. Enterotoxigenic Organisms

    1. J. Holmgren, S. J. S. Hardy, T. R. Hirst, S. Johansson, G. Jonson, J. Sanchez et al.
      Pages 115-124
    2. Yoshifumi Takeda, Shinji Yamasaki, Toshiya Hirayama, Yasutsugu Shimonishi
      Pages 125-138
    3. Monica Thelestam, Mimmi Caspar Shoshan, Carla Fiorentini
      Pages 169-173
  5. Invasive Organisms

    1. P. Helena Mäkelä, Marianne Hovi, Harri Saxén, Anna Muotiala, Petri Riikonen, Marjatta Nurminen et al.
      Pages 175-184
    2. John Stephen, Gillian R. Douce, Iqbal I. Amin
      Pages 185-196
    3. H. Wolf-Watz, Å. Forsberg, R. Rosqvist, I. Bölin, K. Erickson, L. Norlander et al.
      Pages 207-211
    4. Zsuzsa Kienle, Levente Emödy, Torkel Wadström, Paul O’Toole
      Pages 213-215
    5. Tibor Pál, Alf A. Lindbergh
      Pages 223-229
    6. Ivan Ciznar, Firdausi Qadri, Shafiqul Haq, Shaik Abu Hossain
      Pages 231-236
    7. Gerald T. Keusch, Honorine D. Ward, Eduardo Ortega-Barria, Norma Galindo, Miercio E. A. Pereira
      Pages 237-247
    8. Torkel Wadström, Janaki L. Guruge, Shen Wei, Pär Aleljung, Åsa Ljungh
      Pages 249-255
  6. Polymerase Chain Reaction and Other DNA Based Diagnostics of Enteric Infections

    1. Brendan W. Wren, Christopher L. Clayton, Soad Tabaqchali
      Pages 273-278
  7. Vaccine Development

    1. Steven Chatfield, Neil Fairweather, John Tite, Ian Charles, Mark Roberts, Mario Posada et al.
      Pages 279-285
    2. Ann-Mari Svennerholm, Christina Åhrén, Christine Wennerås, Jan Holmgren
      Pages 287-294
  8. Poster Session

    1. Arthur Donohue-Rolfe, David W. K. Acheson, Gerald T. Keusch, Marcia B. Goldberg, Stephanie A. Boyko, Stephen B. Calderwood
      Pages 299-301
    2. Levente Emödy, Åsa Ljungh, Tibor Pal, Géza Sarlós, Torkel Wadström
      Pages 303-306
    3. K. A. Krogfelt, B. A. McCormick, R. L. Burgoff, D. C. Laux, P. S. Cohen
      Pages 317-319
    4. C. J. Luke, T. S. J. Elliott, C. W. Penn
      Pages 321-322
    5. Christine Wennerås, Jan Holmgren, Moyra M. McConnell, Ann-Mari Svennerholm
      Pages 327-330
    6. Agnes E. Wold, Dominique Caugant, Gunilla Lidin-Jansson, Peter de Man, Catharina Svanborg
      Pages 331-333
    7. P. L. Conway, L. Blomberg, A. Welin, P. S. Cohen
      Pages 335-337
  9. Back Matter
    Pages 339-342

About this book


The meeting that provided the material for this book was the 58th Symposium of the Federation of European Microbiological Societies (FEMS) entitled MOLECULAR PATHOGENESIS OF GASTROINTESTINAL INFECTIONS which was held in Helsingor, Denmark from 2nd to 4th September, 1990. The aim of this meeting was to bring together scientists from a range of discipline- microbiology, cell biology, molecular biology and immunology - to consider how microbes, including parasites, colonize and infect the gastrointestinal tract. The programme was designed to focus particular attention on the range of strategies whereby enterovirulent bacteria and parasites colonize the gastrointestinal mucin layer, how they adhere to and penetrate the epithelial layer by entering the cells or passing between them, and how various protein toxins may facilitate these processes. Speakers were especially encouraged to highlight the recent expansion in our knowledge of the molecular mechanisms by which enterotoxigenic and enteropathogenic Escherichia coli, shigellae, salmonellae and Yersinia enterocolitica cause intestinal disease. There were also discussions of recently-discovered gastrointestinal pathogens such as Clostridium difficile and Helicobacter pylori as well as accounts of how virulent determinants can be used to develop new diagnostic methods based on DNA gene probes and the polymerase chain reaction (PCR). These presentations provided the basis for the chapters in this book.


Cytosol Flora Pathogene Toxin development microbe microbiology polymer protein transcription virus

Editors and affiliations

  • T. Wadström
    • 1
  • P. H. Mäkelä
    • 2
  • A.-M. Svennerholm
    • 3
  • H. Wolf-Watz
    • 4
  1. 1.University of LundLundSweden
  2. 2.National Public Health InstituteHelsinkiFinland
  3. 3.University of GothenburgGothenburgSweden
  4. 4.University of UmeåUmeåSweden

Bibliographic information

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