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Phospholipase A2

Role and Function in Inflammation

  • Patrick Y-K Wong
  • Edward A. Dennis

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 275)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Phospholipase A2 Characterization and Role

    1. Keith B. Glaser, Mark D. Lister, Richard J. Ulevitch, Edward A. Dennis
      Pages 1-16
    2. Lorin K. Johnson, Susan Frank, Peter Vades, Waldemar Pruzanski, Aldons J. Lusis, Jeffrey J. Seilhamer
      Pages 17-34
    3. Ruth M. Kramer, Berit Johansen, Catherine Hession, R. Blake Pepinsky
      Pages 35-53
  3. Phospholipase A2 Function

  4. Disease Models for Inflammation

    1. D. W. Morgan, C. Anderson, K. Meyers, J. Coffey, K. Moody, A. Welton
      Pages 145-154
    2. Kathleen R. Gans, Susan R. Lundy, Randine L. Dowling, William M. Mackin, Theresa M. Stevens, Janet S. Kerr
      Pages 155-167
    3. Lisa A. Marshall, Joseph Y. Chang
      Pages 169-182
    4. Bing K. Lam, Chin-Yuh Yang, Patrick Y-K Wong
      Pages 183-191
  5. Back Matter
    Pages 193-199

About this book

Introduction

This volume in the Advances in Experimental Medicine and Biology Series is dedicated to developing an overall view of the "state-of­ the-art" of knowledge in the field of phospholipase A2 and to exploring the role and function of this enzyme in various inflammatory diseases. This book grew out of two major symposia on phospholipase A2 held in 1989: I). "Phospholipase A2: Pathophysiological Role of Soluble and Membrane-Bound Enzymes" organized by Dr. Doug Morgan and Dr. Ann Welton of Hoffmann-La Roche and sponsored by the New York Academy of Sciences (January 24, 1989). II). "Release and Function of Phospholipase A2 from Inflammatory Cells" organized by Dr. Patrick Wong and Dr. Edward Dennis at the FASEB meeting in New Orleans (March 22, 1989). Readers will find exciting advances in our understanding of the structure, function and molecular biology of phospholipase A2 research which is presented in this volume. The elucidation of gene structures of phospholipase A2 should lead to new insights and new approches in the control and regulation of the enzyme activity. This is primary to better understanding the function of phospholipase A2 and the determination of its activity in cellular and animal systems. Of great importance is the development of animal models for inflammatory disease in order to evaluate the role of phospholipase A2 and its inhibitors. We are convinced that this volume will be an excellent reference that surveys this field in which numerous investigators are currently actively at work.

Keywords

biology enzyme enzymes gene membrane molecular biology regulation

Editors and affiliations

  • Patrick Y-K Wong
    • 1
  • Edward A. Dennis
    • 2
  1. 1.New York Medical CollegeValhallaUSA
  2. 2.University of California at San DiegoLa JollaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4684-5805-3
  • Copyright Information Plenum Press, New York 1990
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-5807-7
  • Online ISBN 978-1-4684-5805-3
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site
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