Neutron Beam Design, Development, and Performance for Neutron Capture Therapy

  • Otto K. Harling
  • John A. Bernard
  • Robert G. Zamenhof

Part of the Basic Life Sciences book series (BLSC, volume 54)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Rapporteurs’ Report

    1. Front Matter
      Pages 1-1
    2. R. M. Brugger, G. Constantine, O. K. Harling, F. J. Wheeler
      Pages 3-12
  3. Overviews of Clinical Experience, Clinical Considerations, and Tumor Targeting

    1. Front Matter
      Pages 13-13
    2. H. Madoc-Jones, D. E. Wazer, R. G. Zamenhof, O. K. Harling, J. A. Bernard Jr.
      Pages 23-35
    3. A. H. Soloway, F. Alam, R. F. Barth, A. K. M. Anisuzzaman, B. V. Bapat
      Pages 37-47
  4. Neutron Beam Design

    1. Front Matter
      Pages 49-49
    2. S. D. Clement, J. R. Choi, R. G. Zamenhof, J. C. Yanch, O. K. Harling
      Pages 51-69
    3. F. J. Wheeler, D. K. Parsons, D. W. Nigg, D. E. Wessol, L. G. Miller, R. G. Fairchild
      Pages 83-95
    4. R. M. Brugger, W. H. Herleth
      Pages 153-166
  5. Reactor-Based Neutron Beams

    1. Front Matter
      Pages 167-167
    2. R. G. Fairchild, J. Kalef-Ezra, S. K. Saraf, S. Fiarman, E. Ramsey, L. Wielopolski et al.
      Pages 185-199
    3. J. R. Choi, S. D. Clement, O. K. Harling, R. G. Zamenhof
      Pages 201-218
    4. J. L. Russell Jr., W. H. Miller, R. M. Brugger, W. H. Herleth
      Pages 219-227
    5. G. K. Becker, Y. D. Harker, L. G. Miller, R. A. Anderl, F. J. Wheeler
      Pages 235-245
  6. Accelerator-Based Neutron Beams

    1. Front Matter
      Pages 247-247
    2. E. Grusell, H. Condé, B. Larsson, T. Rönnqvist, O. Sornsuntisook, J. Crawford et al.
      Pages 249-258
  7. Dosimetry and Treatment Planning

    1. Front Matter
      Pages 281-281
    2. R. G. Zamenhof, S. D. Clement, O. K. Harling, J. F. Brenner, D. E. Wazer, H. Madoc-Jones et al.
      Pages 283-305
    3. S. K. Saraf, J. Kalef-Ezra, R. G. Fairchild, B. H. Laster, S. Fiarman, E. Ramsey
      Pages 307-316
    4. D. N. Slatkin, J. A. Kalef-Ezra, S. K. Saraf, D. D. Joel
      Pages 317-320
  8. Back Matter
    Pages 341-353

About this book


For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan between 1968 and 1989 and overviews of clinical considerations for neutron capture therapy and of the status of tumor targeting chemical agents for Ncr. Five contributed poster papers dealing with NCT beam design and performance were also presented. A rapporteurs' paper was prepared after the Workshop to attempt to summarize the major aspects, issues, and conclusions which resulted from this Workshop. Many people contributed to both the smooth functioning of the Workshop and to the preparation of these proceedings. Special thanks are reserved for Ms. Dorothy K.


brain development dosimetry radiation therapy tumor

Editors and affiliations

  • Otto K. Harling
    • 1
  • John A. Bernard
    • 1
  • Robert G. Zamenhof
    • 2
  1. 1.Nuclear Reactor LaboratoryMassachusetts Institute of TechnologyCambridgeUSA
  2. 2.Department of Radiation Oncology, Medical Physics DivisionTufts — New England Medical CenterBostonUSA

Bibliographic information

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