The Respiratory Burst and Its Physiological Significance

  • Anthony J. Sbarra
  • Robert R. Strauss

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Niels Borregaard
    Pages 1-31
  3. Giorgio Berton, Stefano Dusi, Paolo Bellavite
    Pages 33-52
  4. Dirk Roos, René Lutter, Ben G. J. M. Bolscher
    Pages 53-76
  5. Barbara Styrt, Mark S. Klempner
    Pages 77-98
  6. Myron S. Cohen, Bradley E. Britigan
    Pages 99-116
  7. Aldo Dobrina, Pierluigi Patriarca
    Pages 117-140
  8. Giuliano Zabucchi, Renzo Menegazzi, Pierluigi Patriarca
    Pages 141-157
  9. Arthur L. Sagone Jr.
    Pages 159-190
  10. Stanley D. Somerfield, Emil Skamene
    Pages 191-201
  11. Peter J. O’Brien
    Pages 203-232
  12. Arthur L. Sagone Jr.
    Pages 245-276
  13. Leo I. Gordon, Sigmund A. Weitzman
    Pages 277-298
  14. Jeffrey S. Warren, Peter A. Ward, Kent J. Johnson
    Pages 299-314
  15. Jan Maciej Zgliczyński, Teresa Stelmaszyńska
    Pages 315-347
  16. Rudolf E. Schopf
    Pages 349-371
  17. József T. Nagy, Tamás Fülöp Jr., George Paragh, Gabriella Fóris
    Pages 373-383
  18. Eric E. Turner, Bennett M. Shapiro
    Pages 385-403
  19. George Paragh, Éva M. Kovács, József T. Nagy, Gabriella Foŕis, Tamás Fülöp Jr.
    Pages 405-418
  20. Tamás Fülöp Jr., Gabriella Fóris, József T. Nagy, Zsuzsa Varga, András Leövey
    Pages 419-435
  21. Curtis L. Cetrulo, Anthony J. Sbarra, Anjan Chaudhury, Mark T. Peters, Charles J. Lockwood, Gail Thomas et al.
    Pages 437-447
  22. Victor A. Najjar
    Pages 449-466
  23. Back Matter
    Pages 467-476

About this book


When phagocytes are exposed to a number of different stimuli, they undergo dra­ matic changes in the way they process oxygen. Oxygen uptake increases markedly, frequently more than 50-fold; the phagocytes begin to produce large quantities of superoxide and hydrogen peroxide; and they immediately begin to metabolize large amounts of glucose by way of the hexose monophosphate shunt. This series of changes has become known as the respiratory burst. It was first believed that the major function of this respiratory burst was to generate powerful antibacterial agents by the partial reduction of oxygen. It is becoming apparent that the respiratory burst has much wider application, and its physiological function in many different biolog­ ical areas is clear. In this volume, we have attempted to bring together the work of experts who have published extensively on the involvement of the respiratory burst in different physiological functions. In the first three chapters, Dr. Borregaard and Dr. Berton and co-workers and Dr. Roos and co-workers bring together what is known about the respiratory burst. They present up-to-date versions of the biochemical and metabolic activities associ­ ated with the burst. In Chapter 4, Dr. Styrt and Dr. Klempner discuss the respiratory burst as it affects cellular ion homeostasis. Dr. Cohen and Dr. Britigan (Chapter 5) present some interesting data on the competition between the respiratory burst and bacteria for oxygen. Dr. Dobrina and Dr.


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Editors and affiliations

  • Anthony J. Sbarra
    • 1
    • 2
  • Robert R. Strauss
    • 3
  1. 1.St. Margaret’s Hospital for WomenBostonUSA
  2. 2.Tufts University School of MedicineBostonUSA
  3. 3.Clinical Pathology Facility, Inc.PittsburghUSA

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