© 1986

Biophysics of the Pancreatic β-Cell

  • Illani Atwater
  • Eduardo Rojas
  • Bernat Soria

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 211)

Table of contents

  1. Front Matter
    Pages i-xii
  2. New Experimental Approaches

  3. K-Channels

    1. F. M. Ashcroft, D. E. Harrison, S. J. H. Ashcroft
      Pages 53-62
    2. D. L. Cook, C. N. Hales, L. S. Satin
      Pages 63-67
    3. M. L. J. Ashford, N. C. Sturgess, D. L. Cook, C. N. Hales
      Pages 69-76
    4. O. H. Petersen, I. Findlay, M. J. Dunne
      Pages 77-82
    5. J. C. Henquin, M. G. Garrino, M. Nenquin, G. Paolisso, M. Hermans
      Pages 83-93
    6. R. M. Santos, H. Finol, E. Rojas
      Pages 109-123
    7. J. Lopez-Barneo, L. Tabares, A. Castellano
      Pages 125-137
  4. Ca-Channels

  5. Role of Ionic Channels

    1. P. C. Croghan, C. M. Dawson, A. M. Scott, J. A. Bangham
      Pages 207-223

About this book


Pancreatic a-cell biophysics has undergone a veritable informa­ tion explosion in the past two years. Single channel and macroscopic currents have become easily accessible following the introduction of the patch clamp technique. In addition to this new approach, further development of techniques for optical measurements, ion-sensitive microelectrodes, permeabilized cells and mathematical modelling have recently added to the now classical techniques of membrane potential recording and tracer flux measurement. The International Workshop on Biophysics of the Pancreatic a-Cell held in Alicante (Spain) on Sep­ tember 30 - October 1, 1985, has now given us the opportunity to share experiences with these new techniques applied to the a-cell. Further­ more this was the first occasion for most of the groups doing patch­ clamp studies of the a-cell to decide on appropriate nomenclature and to debate the different characteristics of the a-cell ionic channels. To make this information available to the larger scientific community a record of the meeting has been assembled in this book. It is a collection of research papers by leading scientists at the meet­ ing working on biophysical, biochemical and physiological aspects. of secretion. We grouped their contributions in seven sections, includ­ ing new experimental approaches, K-channels, Ca-channels, role of ionic channels, intracellular ionized calcium, neural regulation and mechanisms of insulin release. Each section gives an account of the state of the problem at the time of the meeting, and the subjects are analyzed from the different perspectives of the various contributors.


Calcium biophysics cells membrane regulation

Editors and affiliations

  • Illani Atwater
    • 1
  • Eduardo Rojas
    • 1
  • Bernat Soria
    • 2
  1. 1.National Institutes of HealthBethesdaUSA
  2. 2.University of AlicanteAlicanteSpain

Bibliographic information

  • Book Title Biophysics of the Pancreatic β-Cell
  • Authors Illani Atwater
    Eduardo Rojas
    Bernat Soria
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Springer-Verlag US 1986
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42555-4
  • Softcover ISBN 978-1-4684-5316-4
  • eBook ISBN 978-1-4684-5314-0
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XII, 494
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cell Biology
    Medical Biochemistry
  • Buy this book on publisher's site
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