Amyotrophic Lateral Sclerosis

1. Diagnostic Tools

   1. Light and Ultrastructural Studies in Sural Biopsies of the Pseudopolyneuropathic form of ALS

      • G. Di Trapani, P. David, A. La Cara, P. Tonali, P. Laurienzo

      Pages 111-119

   2. Prosody Alterations in Amyotrophic Lateral Sclerosis

      • S. Congia, S. Di Ninni, F. Zonza, M. Melis

      Pages 121-123

   3. Analysis of Extrinsic Factors Affecting Pallestesic Threshold (VT) Of Amyotrophic Lateral Sclerosis Patients

      • M. L. Delodovici, E. Terazzi, C. Pasetti, P. Pinelli

      Pages 125-128

   4. Spinal Cord Electrophysiological Activities After Small Doses of TRH in Control Subjects and ALS Patients

      • P. J. Delwaide, J. Schoenen

      Pages 129-133

   5. Osmotic Haemolysis in Amyotrophic Lateral Sclerosis

      • S. Galli, A. Sessa, G. Pirotta, L. De Caro, M. Poloni, L. Mazzini et al.

      Pages 135-137

   6. Some Remarks on Lung Function in Amyotrophic Lateral Sclerosis

      • F. Ioli, G. Di Lorenzo, C. F. Donner, C. Fracchia, A. Patessio

      Pages 139-142

   7. CT-Scanning of Skeletal Muscles in Amyotrophic Lateral Sclerosis

      • G. Küther, S. O. Rodiek, A. Struppler

      Pages 143-148

   8. Immunological Assessment in Sporadic Amyotrophic Lateral Sclerosis (ALS)

      • L. Provinciali, A. R. Giovagnoli, S. Battucci, C. Bartocci, M. Montroni

      Pages 149-153

   9. Changes in the Normal Pattern of H-Reflex Inhibition During Muscle Release in ALS

      • M. Schieppati, A. Nardone, M. Poloni

      Pages 155-158

   10. Atypical Forms of Familial Amyotrophic Lateral Sclerosis

       • N. Gregoire, G. Serratrice

       Pages 159-164

2. Clinical Management of ALS

   1. Front Matter

      Pages 165-165

      PDF

   2. The Management of Motor Neurone Disease

      • F. C. Rose

      Pages 167-174

   3. The Treatment of Amyotrophic Lateral Sclerosis

      • F. H. Norris, R. A. Smith, E. H. Denys

      Pages 175-182

   4. Nutritional Supplements in Amyotrophic Lateral Sclerosis

      • F. H. Norris, E. H. Denys

      Pages 183-189

   5. Respiratory Monitoring and Treatment: Objective Treatments Using Non-Invasive Measurements

      • R. J. Fallat, F. H. Norris, D. Holden, K. Kandal, P. C. Roggero

      Pages 191-200

   6. Management of Bulbar Symptoms in Amyotrophic Lateral Sclerosis

      • A. D. Hillel, R. M. Miller

      Pages 201-221

   7. Clinico-Pathological Studies of Long Survival ALS Cases Maintained by Active Life-Support Measures

      • M. Iwata

      Pages 223-225

   8. First Results with Percutaneous Endoscopic Gastrostomy

      • M. Keymling

      Pages 227-229

   9. Home Nursing Care by Families for Severely Paralyzed ALS Patients

      • F. H. Norris, D. Holden, K. Kandal, E. Stanley

      Pages 231-238

   10. Physical Therapy and Rehabilitation Techniques for Patients with Amyotrophic Lateral Sclerosis

       • M. Sinaki

       Pages 239-252

An International Conference on "Therapeutic. Psychological and Research Aspects of Amyotrophic Lateral Sclerosis" was held in Varese. Italy from the 27th to the 31st March 1985. Health care professionals. scientists. patients and their families from twenty countries around the world participated in this meeting. The objectives of the Varese conference were the following: a. To provide a forum for the proponents of the various paths of research into ALS. b. To correlate the useful therapies employed regionally. for the purpose of developing a common guide for patients, families, and supporting professionals. c. To encourage self-examination by the health care professionals into the psychological barriers imposed by a diagnosis of terminal illness for which there is no known cause or cure. Not surprisingly, there were no announcements of "breakthroughs" or "miracle cures", which are nonetheless hoped for in the confrontation of a disease such as ALS. It is fair to say, however, that Varese provided the context for a thorough review of what is known about ALS and we hope that the papers will renew some of the enthusiasm which has characterized this conference. The book contains six sections: Basic Research Aspects, Diagnostic Tools, Clinical Management, Therapeutic Trials, Psychological Aspects and the Epidemiology of ALS. Certain aspects, such as pathological studies and animal models, have not been covered; these subjects were partially treated during the informal sessions. Nevertheless, the large number of papers bears evidence to the growing interest in ALS and to the success of the Varese meeting.

• Therapeut
• Therapie
• diagnosis
• epidemiology
• management

• University of Pavia, Pavia, Italy

  V. Cosi

• University Medical Center, Geneva, Switzerland

  Ann C. Kato

• ALS/MND Research Foundation, Zurich, Switzerland

  W. Parlette

• University of Milan, Milan, Italy

  P. Pinelli, M. Poloni

Policies and ethics