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Gene Expression in Muscle

  • Book
  • © 1985

Overview

Editors:
  1. Richard C. Strohman

    1. University of California, Berkeley, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Stewart Wolf

    1. Totts Gap Medical Research Laboratories, Bangor, USA
      Temple University, Philadelphia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 182)

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Table of contents (32 chapters)

  1. Regulating Expression of Protein Isoforms

    1. Front Matter

      Pages 201-201
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    2. Overview

      • Donald A. Fischman, David Bader, Takashi Obinata
      Pages 203-214

    3. Myosins A & B in the Organization of Myofilaments

      • Henry F. Epstein
      Pages 215-222

    4. A Set of Actin-Filament Associated Proteins Characterized by Quantitative Two-Dimensional Gel Electrophoresis

      • James I. Garrels, Shigeko Yamashiro-Matsumura, Jim J.-C. Lin, Fumio Matsumura
      Pages 223-230

    5. Muscle Gene Expression in Heterokaryons

      • Helen M. Blau, Choy-Pik Chiu, Grace K. Pavlath, Cecelia Webster
      Pages 231-247

    6. Myosin Isozyme Transitions in Developing and Regenerating Rat Muscle

      • Robert G. Whalen, Gillian S. Butler-Browne, Lawrence B. Bugaisky, John B. Harris, Danielle Herliocoviez
      Pages 249-257

    7. Myosin Expression During Regeneration and in Denervated Skeletal Muscle

      • Richard C. Strohman, Ryoichi Matsuda
      Pages 259-263

    8. Parvalbumin Reduction in Relation to Possible Perturbations of CA2+ -Homeostasis in Muscular Dystrophy

      • Dirk Pette, Gary Klug, Heinz Reichmann
      Pages 265-267

    9. Myosin Isozymes in Developing Chicken Muscles

      • Susan Lowey
      Pages 269-280

  2. Recombinant DNA Approaches in the Investigation of Muscle Gene Expression

    1. Front Matter

      Pages 281-281
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    2. Introduction

      • Henry F. Epstein
      Pages 283-285

    3. Genetic Analysis of Duchenne Dystrophy

      • Louis Kunkel, Gail Burns, Jeff Aldrige, Samuel Latt
      Pages 287-294

    4. The Chromosomal Assignment of Muscle-Specific Genes

      • David Yaffe, Uri Nudel, Henryk Czosnek, Danielle Melloul, Batya Aloni
      Pages 295-307

    5. Expression of Isoforms from Cloned Skeletal and Cardiac Actin Genes

      • Laurence H. Kedes
      Pages 309-332

    6. The Actin and Myosin Multigene Families

      • M. Buckingham, S. Alonso, G. Bugaisky, P. Barton, A. Cohen, P. Daubas et al.
      Pages 333-344

    7. Multigene Families, Differential Transcription and Differential Splicing: Different Origin of Contractile Isoproteins in Muscle

      • Emmanuel E. Strehler
      Pages 345-355

  3. Summary and Synthesis

    1. Front Matter

      Pages 357-357
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    2. Summary and Synthesis

      • R. Rodney Howell
      Pages 359-361

  4. Coda

    1. Coda

      • Richard C. Strohman, Stewart Wolf
      Pages 363-366

  5. Back Matter

    Pages 367-434
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Keywords

About this book

This volume contains the edited transcript of an interdisci­ plinary colloquium held at Totts Gap Medical Research Laboratories, Bangor, Pennsylvania on October 12-14, 1983 under the sponsorship of the Muscular Dystrophy Association. The aim was to illuminate the pathogenic mechanism of Duchenne Muscular Dystrophy through a synthesis of available data on gene expression in muscle. In the informal give and take ot the collo­ quium, the participants found themselves engaged in mutual education and enlightenment as they attempted to put together what is known and to highlight what is not known about the subject. Significant research into muscle as a tissue and muscle disease began only about 50 years ago although the description of muscular dystrophy by Guillaume Benjamin Amand Duchenne de Boulogne had been published in 1862. By 1943 it was clear that Duchenne muscular dystrophy was an X-linked genetic disorder. Up to the present, however, the offending gene has not been identified although its location on the short arm of the X chromosome has been approximately determined. The gene product associated with the initial disturbance in skeletal muscle has also remained elusive up to now. Moreover, investigations into the mechanisms of the muscle degeneration have been hampered by ignorance of the fundamental phenotypic expression of the genetic disorder.

Editors and Affiliations

  • University of California, Berkeley, USA

    Richard C. Strohman

  • Totts Gap Medical Research Laboratories, Bangor, USA

    Stewart Wolf

  • Temple University, Philadelphia, USA

    Stewart Wolf

Bibliographic Information

  • Book Title: Gene Expression in Muscle

  • Editors: Richard C. Strohman, Stewart Wolf

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-4907-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1985

  • Softcover ISBN: 978-1-4684-4909-9Published: 27 December 2012

  • eBook ISBN: 978-1-4684-4907-5Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 434

  • Topics: Human Genetics

  • Industry Sectors: Biotechnology, Pharma

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