Genetic and Phenotypic Markers of Tumors

  • Stuart A. Aaronson
  • Luigi Frati
  • Roberto Verna

Table of contents

  1. Front Matter
    Pages i-xi
  2. Introduction

    1. Luigi Frati, Enrico Cortesi, Corrado Ficorella, Vittorio Manzari, Roberto Verna
      Pages 1-20
  3. Phenotypic Markers

    1. Biochemical Markers

      1. Paolo Marchetti, Enrico Cortesi, Corrado Ficorella, Luigi Frati
        Pages 21-25
      2. Filiberto Cimino, Tommaso Russo, Alfredo Colonna, Francesco Salvatore
        Pages 27-39
      3. L. Santamaria, N. Katopodis, G. Santagati, A. Bianchi, R. Pizzala, C. C. Stock
        Pages 41-47
      4. I. Ricciardi, S. De Placido, C. Pagliarulo, G. Delrio, F. Citarella, L. De Sio et al.
        Pages 67-74
      5. Marco Ruggiero, Gabriella Fibbi, Mario Del Rosso, Simonetta Vannucchi, Franca Pasquali, Vincenzo Chiarugi
        Pages 75-79
      6. Gabriella Fibbi, Vincenzo Chiarugi, Mario Del Rosso
        Pages 81-84
    2. Detection of Antigenic Markers by Monoclonal Antibodies

      1. J. Schlom, D. Colcher, P. Hand, D. Wunderlich, M. Nuti, R. Mariani-Costantini et al.
        Pages 91-105
      2. M. I. Colnaghi, S. Mènard, R. Mariani-Costantini, S. Canevari, S. Miotti, G. Della Torre et al.
        Pages 107-115
      3. Raffaella Muraro, David Wunderlich, Jeffrey Schlom
        Pages 117-127
    3. Cellular Recognition of Phenotypic Markers

      1. C. Riccardi, G. Migliorati, L. Frati, F. Guadagni, E. Bonmassar, R. B. Herberman
        Pages 129-137
      2. Francesco Bistoni, Manuela Baccarini, Lucia Scaringi, Rosanna Mazzolla, Paolo Puccetti, Pierfrancesco Marconi
        Pages 139-144
      3. Pierfrancesco Marconi, Lucia Scaringi, Antonio Cassone, Luciana Tissi
        Pages 145-151
      4. Clara Ausiello, Giulio Spagnoli, Francesca Mondello, Pierfrancesco Marconi, Francesco Bistoni, Antonio Cassone
        Pages 153-157
      5. Guido Forni, Mirella Giovarelli, Susanna Cerruti Sola, Angela Santoni
        Pages 159-173
      6. Mario Piccoli, Angela Santoni, Francesca Velotti, M. Cristina Galli, Luigi Frati, Michael A. Chirigos
        Pages 175-187
      7. Alberto Faggioni, Giuseppe Barile, Mario Piccoli, Luigi Frati
        Pages 189-197
    4. Modulation of Antigenic Expression

      1. G. Graziani, C. Grandori, B. Macchi, S. Pastore, E. Bonmassar, A. Giuliani Bonmassar
        Pages 199-210
      2. A. Dolei, F. Ameglio, M. R. Capobianchi, R. Tosi
        Pages 211-216
      3. M. R. Capobianchi, F. Ameglio, R. Tosi, A. Dolei
        Pages 217-221
      4. G. M. Pontieri, L. Lenti, M. Lipari, D. Lombardi, A. Zicari, F. Ippoliti et al.
        Pages 223-233
      5. V. Tomasi, R. Mastacchi, G. Bartolini, S. Fadda, O. Barnabei, R. Gatto et al.
        Pages 235-259
  4. Genomic Markers

    1. Stuart A. Aaronson, Yasuhito Yuasa, Keith C. Robbins, Alessandra Eva, Rosita Gol, Steven R. Tronick
      Pages 261-277
    2. P. P. Di Fiore, A. Fusco, G. Colletta, A. Pinto, M. Ferrentino, V. De Franciscis et al.
      Pages 279-289
    3. A. Fusco, P. P. Di Fiore, M. T. Berlingieri, G. Colletta, A. M. Cirafici, G. Portella et al.
      Pages 291-296
    4. F. G. Giancotti, M. F. Di Renzo, P. C. Marchisio, G. Tarone, G. Tarone, L. Naldini et al.
      Pages 297-303
    5. C. Peschle, F. Mavilio, N. M. Sposi, A. Giampaolo, A. Caré, L. Bottero et al.
      Pages 311-321
    6. G. Migliaccio, L. Avitabile, A. R. Migliaccio, S. Petti, R. Guerriero, G. Mastroberardino et al.
      Pages 323-330
    7. Oliviero E. Varnier, Giorgio Ivaldi, Proto Pippia, Olimpio Muratore, Stephen P. Raffanti, Suraiya Rasheed
      Pages 331-335
    8. F. Wong-Staal, G. Franchini, B. Hahn, S. Arya, E. P. Gelmann, V. Manzari et al.
      Pages 337-344
    9. Vito M. Fazio, Vittorio Manzari, Luigi Frati, Genoveffa Franchini, Flossie Wong-Staal, Robert C. Gallo
      Pages 345-355
  5. Back Matter
    Pages 373-379

About this book


The study of tumor markers is not only one of the most important but also one that offers one of the richest perspectives in biology and clinical oncology. The aim of scientists in this field is to adduce evidence of a property that is typical of and exclusive to tumor cells, and which is easy to determine, in order to immediately recognize, or even better, to foresee, neoplastic transformations. Unfortunately, despite the large number of scientists and laboratories engaged in this work, the ideal tumor marker has not yet been identified. However, it is worth noting that new trends in molecular biology and immunovirology have recently opened up new avenues that may lead to the eventual resolution of this problem. In this book, different approaches to the identification of tumor markers, from the points of view of biochemistry, immunology, and molecular biology, are compared in order to explore possible interrelationships and to stimulate scientific collaboration among scientists active in these fields, both in basic research and in clinical applications. We wish to thank all the contributors and also the publisher, especially Dr. Robert Andrews, for making the publication of this book possible.


antibody antigen biology cells immunology immunotherapy interferon leukemia lymphocytes molecular biology oncology research tumor virology virus

Editors and affiliations

  • Stuart A. Aaronson
    • 1
  • Luigi Frati
    • 2
  • Roberto Verna
    • 2
  1. 1.National Cancer InstituteNational Institutes of HealthBethesdaUSA
  2. 2.Institute of General PathologyRomeItaly

Bibliographic information

Industry Sectors
Health & Hospitals
Consumer Packaged Goods