Immunomodulation by Bacteria and Their Products

  • Herman Friedman
  • Thomas W. Klein
  • Andor Szentivanyi

Table of contents

  1. Front Matter
    Pages i-xii
  2. Arthur G. Johnson
    Pages 1-11
  3. J. J. Oppenheim, P. S. Steeg, R. N. Moore
    Pages 13-21
  4. Alison D. O’Brien, David L. Rosenstreich, Irwin Scher
    Pages 37-48
  5. John H. Schwab, Dena L. Toffaletti, Roger R. Brown
    Pages 49-57
  6. Edgar E. Hanna, Martha L. Hale, Michael L. Misfeldt
    Pages 59-75
  7. A. Ghaffar, R. D. Paul, M. M. Sigel, W. Lichter, L. L. Wellham
    Pages 135-149
  8. U. H. Behling, A. Nowotny
    Pages 165-179
  9. R. Christopher Butler, Alois Nowotny, Herman Friedman
    Pages 181-197
  10. T. K. Eisenstein, C. R. Angerman, L. W. Deakins
    Pages 199-214
  11. David L. Rosenstreich, Stefanie N. Vogel
    Pages 215-229
  12. Shozo Kotani, Haruhiko Takada, Masachika Tsujimoto, Tomohiko Ogawa, Keijiro Kato, Takafumi Okunaga et al.
    Pages 231-273
  13. Thomas Klein, William Benjamin, Alvin Winters, Herman Friedman
    Pages 275-292
  14. J. Terrell Hoffeld, Zvi Metzger, Joost J. Oppenheim
    Pages 293-304
  15. Back Matter
    Pages 305-308

About this book


It is almost axiomatic that an explosive increase in knowledge and interest concerning host immune defense mechanisms and the immune response system in general is occurring. Many new developments are evident at the interphase between the areas of immunology, infectious diseases, and host defenses to microorganisms. It is now widely rec­ ognized that a functioning host immune defense system consists of a variety of lymphoid cells. These include effector and affector cells consisting of both Band T cells and their progeny. Mononuclear phago­ cytes which are widely distributed throughout the body are also intimately involved in these processes. These cells are involved not only in the clearance of particulate matter including bacteria, viruses and fungi, but also presumably in host defense against neo­ plasia. Among the many triumphs of the biological revolution over the past decade or so is the rapidly developing understanding of how these cells and their products, including antibody, lymphokines, monokines, etc. , function and interact. It is now recognized that although the immune defense system is involved in defense against infectious agents, it is also now be­ coming quite clear that many infectious agents, including bacteria, viruses and fungi, as well as their products, can interact with the immune response system. For example, it has been long recognized that many of the "adjuvants" which enhance the immune responses in nonspecific ways are derived from microorganisms. Microbial products have marked effects on the immume response system.


antibody cell fungi immunology infection infectious disease vaccine

Editors and affiliations

  • Herman Friedman
    • 1
  • Thomas W. Klein
    • 1
  • Andor Szentivanyi
    • 1
  1. 1.University of South FloridaTampaUSA

Bibliographic information

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