Protein Crosslinking

Biochemical and Molecular Aspects

  • Mendel Friedman

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 86A)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Gary Gustafson, Clarence A. Ryan
    Pages 31-42
  3. D. B. Wetlaufer, V. P. Saxena, A. K. Ahmed, S. W. Schaffer, P. W. Pick, K.-J. Oh et al.
    Pages 43-50
  4. Hiroshi Taniuchi, A. Seetharama Acharya, Generoso Andria, Diana S. Parker
    Pages 51-65
  5. F. R. Huebner, J. A. Bietz, J. S. Wall
    Pages 67-88
  6. Danute E. Nitecki, Virgil Woods, Joel W. Goodman
    Pages 139-148
  7. Rosa Uy, Finn Wold
    Pages 169-186
  8. Wolfgang E. Trommer, Klaus Friebel, Hans-Hermann Kiltz, Hans-Jörg Kolkenbrock
    Pages 187-195
  9. Robert R. Traut, James W. Kenny
    Pages 215-233
  10. Dietrich Brandenburg, Hans-Gregor Gattner, Winrich Schermutzki, Achim Schüttler, Johanna Uschkoreit, Josef Weimann et al.
    Pages 261-282
  11. John A. Rupley, Robert E. Johnson, Patricia H. Adams
    Pages 295-306
  12. Klaus Ziegler, Irene Schmitz, Helmut Zahn
    Pages 345-354
  13. Sandra J. Tillin, Richard A. O’Connell, Allen G. Pittman, Wilfred H. Ward
    Pages 383-390
  14. Myron L. Bender, A. B. Cottingham, Lee K. Sun, K. Tanizawa
    Pages 405-413
  15. J. W. Harlan, S. H. Feairheller
    Pages 425-440
  16. Rao S. Rapaka, D. E. Nitecki, Rajendra S. Bhatnagar
    Pages 473-490
  17. Rajendra S. Bhatnagar, Rao S. Rapaka, V. S. Ananthanarayanan
    Pages 491-507
  18. Robert Shapiro, Aviv Gazit
    Pages 633-640
  19. David P. Kelly, M. K. Dewar, R. B. Johns, Shao Wei-Let, J. F. Yates
    Pages 641-647
  20. Munenori Sakamoto, Fumitaka Nakayama, Koh-Ichi Kajiyama
    Pages 687-712
  21. Mendel Friedman
    Pages 713-726
  22. Back Matter
    Pages 745-760

About this book


The word crosslinking implies durable combination of (usually large) distinct elements at specific places to create a new entity that has different properties as a result of the union. In the case of proteins, such crosslinking often results in important changes in chemical, functional, nutritional, and biomedical properties, besides physical properties simply related to molecular size and shape. (Nucleic acids, carbohydrates, and other biopolymers are correspondingly affected.) Since proteins are ubiquitous, the consequences of their crosslinking are widespread and often profound. Scientists from many disciplines including organic chemistry, bio­ chemistry, protein chemistry, food science, nutrition, radiation biology, pharmacology, physiology, medicine, and dentistry are, therefore, minutely interested in protein crosslinking reactions and their implications. Because protein crosslinking encompasses so many disciplines, in organizing the Symposium on Nutritional and Biochemical Conse­ quences of Protein Crosslinking sponsored by the Protein Subdivi­ sion of the Division of Agricultural and Food Chemistry of the American Chemical Society, I sought participants with the broadest possible range of interests, yet with a common concern for theore­ tical and practical aspects of protein crosslinking. An important function of a symposium is to catalyze progress by bringing together ideas and experiences needed for interaction among different, yet related disciplines. To my pleasant surprise, nearly everyone invited came to San Francisco to participate.


biology carbohydrates chemistry fish food food chemistry medicine nucleic acid nucleic acids nutrition pharmacology physiology protein radiation system

Editors and affiliations

  • Mendel Friedman
    • 1
  1. 1.Western Regional Research LaboratoryAgricultural Research Service U.S. Department of AgricultureBerkeleyUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag US 1977
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-3284-8
  • Online ISBN 978-1-4684-3282-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site