Red Cell Metabolism and Function

Proceedings of the First International Conference on Red Cell Metabolism and Function, held at the University of Michigan, Ann Arbor, October 1–3, 1969

  • George J. Brewer

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 6)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Relationship Between Red Cell Metabolism and Function

  3. Metabolic Control Mechanisms in the Red Cell

    1. Front Matter
      Pages 115-115
    2. A. Chanutin, Chairman

  4. Interaction of the Cardiac, Pulmonary, and Erythrocyte Systems in Respiratory Homeostasis

    1. Front Matter
      Pages 175-175
    2. R. Grover, Chairman

      1. Giles F. Filley
        Pages 177-190
      2. Robert F. Grover, John V. Weil
        Pages 191-201
      3. C. Lenfant, J. D. Torrance, R. Woodson, C. A. Finch
        Pages 203-212
      4. John A. Faulkner, George J. Brewer, John W. Eaton
        Pages 213-227
  5. Erythrocyte Function after Blood Storage

  6. Back Matter
    Pages 319-390

About this book


In the last six years, a remarkable series of stUdies have demonstrated an intimate relationship between red cell metabolism and the function of the cell as an organ of gas transport. First came the demonstration of binding of organic phosphocompounds of the red cell to hemoglobin; this was followed by studies that demonstrated modification of hemoglobin oxygen affinity by such binding. At present we are in an exhilirating phase of accrual of data showing that the levels of these phosphorylated inter­ mediates can be rapidly altered in the red cell to modulate hemo­ globin function. At one time it was said that the red cell was an inert bag full of hemoglobin. Now we know not only that the cell has an active metabolism crucial to its viability, but that this metabolism is just as crucial to the whole organism in the proper adjustment of oxygen transport. On October first, second and third, 1969, red cell biochemists, general biochemists, geneticists, cardio-pulmonary physiologists, exercise physiologists, experts in blood storage, and represen­ tatives from many other disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor, to present recent findings and discuss developments in this new interdisciplinary field. The meeting was dedicated to Dr. Alfred Chanutin, Professor Emeritus of the University of Virginia, to honor his retirement in 1967 and in recognition of his great contributions to the studies outlined in the first paragraph of this preface.


adaptation blood blood cell cell cognition development education erythrocyte hypoxia medical education metabolism organ transport

Editors and affiliations

  • George J. Brewer
    • 1
  1. 1.Departments of Human Genetics and Medicine (Simpson Memorial Institute)University of MichiganAnn ArborUSA

Bibliographic information

  • DOI
  • Copyright Information Plenum Press, New York 1970
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4684-3197-1
  • Online ISBN 978-1-4684-3195-7
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology