© 1987


  • Michael M. C. Lai
  • Stephen A. Stohlman

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 218)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Coronaviruses: A Historical Perspective

    1. Leslie P. Weiner
      Pages 1-5
  3. Molecular Biology of Coronaviruses

    1. Michael M. C. Lai
      Pages 7-13
    2. M. E. G. Boursnell, T. D. K. Brown, I. J. Foulds, P. F. Green, F. M. Tomley, M. M. Binns
      Pages 15-29
    3. R. J. de Groot, J. A. Lenstra, W. Luytjes, H. G. M. Niesters, M. C. Horzinek, B. A. M. van der Zeijst et al.
      Pages 31-38
    4. A. R. Smith, M. E. G. Boursnell, M. M. Binns, T. D. K. Brown, S. C. Inglis
      Pages 47-54
    5. P. J. Bredenbeek, J. Charite, J. F. A. Noten, W. Luytjes, M. C. Horzinek, B. A. M. van der Zeijst et al.
      Pages 65-72
    6. Lisa H. Soe, Chien-Kou Shieh, Shinji Makino, Ming-Fu Chang, Stephen A. Stohlman, Michael M. C. Lai
      Pages 73-81
    7. Heiner Niemann, Thomas Mayer, Manfred Wirth, Teruko Tamura
      Pages 83-97
    8. James G. Keck, Shinji Makino, Lisa H. Soe, John O. Fleming, Stephen A. Stohlman, Michael M. C. Lai
      Pages 99-107
    9. Denis Rasschaert, Bernard Delmas, Bernard Charley, Jeanne Grosclaude, Jacqueline Gelfi, Hubert Laude
      Pages 109-116
    10. Paul A. Kapke, Frank Y. C. Tung, David A. Brian, Roger D. Woods, Ronald Wesley
      Pages 117-122
    11. Brenda G. Hogue, David A. Brian
      Pages 131-136
    12. Ralph S. Baric, Chien Kou Shieh, Stephen A. Stohlman, Michael M. C. Lai
      Pages 137-149
    13. Fiona Tomley, Matthew Binns, Mike Boursnell, Adrian Mockett
      Pages 151-153
    14. James G. Keck, Brenda G. Hogue, David A. Brian, Michael M. C. Lai
      Pages 157-158

About this book


Coronaviruses have emerged during the past ten years from being a group of viruses causing a variety of minor veterinary and human diseases to a major virus group of both clinical significance and molecular biological interest. Against this background, two international coronavirus symposia were held in 1980 and 1983. In recent years, the pace of coronavirus research has been quickened even more by infusion of recombinant DNA technology and establishment of various animal model systems to study the pathogenesis and immunology of coronavirus infections. We therefore organized the Third International Coronavirus Symposium held at Asilomar, California in September 1986, which was attended by more than 120 participants representing a cross­ section of both academia and industry. This symposium provided an exciting and stimulating forum for assessing the progress made since the last triennial symposium in Netherlands and to suggest the directions for future efforts. This volume collects the scientific papers presented in this symposium. Three loosely defined areas, Molecular biology, Virus-Cell Interaction and Viral Pathogenesis, are separated. These papers very nicely summarize the current status of coronavirus research. They contain a large amount of sequence data, including the complete sequence of a 27 Kb coronavirus genome, a novel mechanism of mRNA synthesis that is unique to coronviruses, and many exciting aspects of coronavirus pathogenesis and immunology. Reflecting the growing interest in the preparation of vaccines, several papers also address the issues related to coronavirus vaccines, which is an area new to this symposium. Dr.


immunology infection molecular biology pathogenesis vaccine virus

Editors and affiliations

  • Michael M. C. Lai
    • 1
  • Stephen A. Stohlman
    • 1
  1. 1.University of Southern California School of MedicineLos AngelesUSA

Bibliographic information

  • Book Title Coronaviruses
  • Editors M. Lai
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Plenum Press, New York 1987
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-42672-8
  • Softcover ISBN 978-1-4684-1282-6
  • eBook ISBN 978-1-4684-1280-2
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XII, 591
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Medical Microbiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Consumer Packaged Goods