Neurotransmitter Interactions and Cognitive Function

  • Edward D. Levin
  • Michael W. Decker
  • Larry L. Butcher

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Paavo J. Riekkinen, Jouni Sirvio, Paavo Riekkinen Jr., Antti Valjakka, Pekka Jakala, Esa Koivisto et al.
    Pages 91-102
  3. V. Haroutunian, A. C. Santucci, K. L. Davis
    Pages 118-143
  4. Edward D. Levin, Roger W. Russell
    Pages 183-195
  5. Carlos Tomaz, Marcus L. Brandao, Norberto Garcia-Cairasco
    Pages 240-256
  6. Thomas J. Walsh, Robert W. Stackman
    Pages 312-328
  7. Martin Sarter, Paul Dudchenko, Holly Moore, Lee Ann Holley, John P. Bruno
    Pages 329-354
  8. Edward D. Levin, Michael Decker, Larry L. Butcher
    Pages 355-357
  9. Back Matter
    Pages 359-362

About this book


JAMES L. MCGAUGH Understanding of the nature and functions of neurotransmitter systems in the brain has increased enormously in recent decades. Lack of knowledge required us, not too long ago, to use the adjective "putative" when discussing transmitters. Such caution is no longer essential (at least for a number of transmitters). Impressive progress has been achieved in understanding the pharmacology, biochemistry and anatomy of transmitter systems. There has, however, been relatively less progress in understanding the functioning of brain transmitters in regulating and mediating behavior. A simple and certainly correct explanation for this is, of course, that understanding of neurotransmitter functions requires prior detailed knowledge of basic pharmacology, biochemistry and anatomy. Beyond that, it now seems likely that progress in understanding the functions of brain neurotransmitters will proceed only as we examine the interactions of neurotransmitter systems in regulating behavioral functions. This premise is, of course, suggested by the findings of studies of the chemical neuroanatomy of the brain: Neurotransmitter systems are influenced by other neurotransmitter systems and, in tum, influence the same as well as other systems. No system works alone. The chapters in this book explicitly examine the interactions of neurotransmitter systems involved in the regulation of cognitive processes. The facts and interpretations offered provide compelling support for the premise that cognitive processes are orchestrated by interactions among neurotransmitter systems. And, they offer promise that understanding of such interactions will be of critical importance in the develop­ ment of treatments for brain diseases affecting cognitive functioning.


anatomy biochemistry brain cognition cortex forebrain neuroanatomy neurons physiology

Editors and affiliations

  • Edward D. Levin
    • 1
  • Michael W. Decker
    • 2
  • Larry L. Butcher
    • 3
  1. 1.Department of PsychiatryDuke University Medical CenterDurhamUSA
  2. 2.Abbott LaboratoriesAbbott ParkUSA
  3. 3.Laboratory of Chemical Neuroanatomy, Department of PsychologyUniversity of CaliforniaLos AngelesUSA

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