Advances in Perinatal Medicine

Volume 5

  • Aubrey Milunsky
  • Emanuel A. Friedman
  • Louis Gluck

Table of contents

  1. Front Matter
    Pages i-xviii
  2. K. Hemminki, M.-L. Lindbohm, H. Taskinen
    Pages 43-91
  3. Ted S. Rosenkrantz, William Oh
    Pages 93-123
  4. Barry S. Zuckerman, Steven J. Parker, Ralph Hingson, Joel J. Alpert, Janet Mitchell
    Pages 125-179
  5. Robert C. Chantigian, Gerard W. Ostheimer
    Pages 181-242
  6. David A. Eschenbach
    Pages 243-264
  7. Back Matter
    Pages 265-280

About this book


The state of health care is reflected by perinatal and neonatal morbidity and mortality as well as by the frequencies of long-term neurologic and developmental disorders. Many factors, some without immediately rec­ ognizable significance to childbearing and many still unknown, undoubt­ edly contribute beneficially or adversely to the outcome of pregnancy. Knowledge concerning the impact of such factors on the fetus and sur­ viving infant is critical. Confounding analyses of pregnancy outcome, especially these past two or three decades, are the effects of newly un­ dertaken invasive or inactive therapeutic approaches coupled with the advent of high technology. Many innovations have been introduced with­ out serious efforts to evaluate their impact prospectively and objectively. The consequences of therapeutic misadventures characterized the past; it seems they have been replaced to a degree by some of the complications of applied technology. Examples abound: after overuse of oxygen was recognized to cause retrolental fibroplasia, its restriction led to an in­ crease in both neonatal death rates and neurologic damage in surviving infants. Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dos­ age, occasionally resulted in kernicterus. Prophylactic sulfonamide use had a similar end result. More recent is the observation of bronchopul­ monary dysplasia as a complication of respirator therapy for hyaline membrane disease.


child childhood complications fetus growth infection monitoring nutrition pain placenta pregnancy

Editors and affiliations

  • Aubrey Milunsky
    • 1
  • Emanuel A. Friedman
    • 2
  • Louis Gluck
    • 3
  1. 1.Boston University School of MedicineBostonUSA
  2. 2.Harvard Medical SchoolBostonUSA
  3. 3.Irvine School of MedicineUniversity of CaliforniaIrvineUSA

Bibliographic information

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