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Molecular Biology and Pathogenesis of Coronaviruses

  • Book
  • © 1984

Overview

Editors:
  1. P. J. M. Rottier

    1. State University of Utrecht, Utrecht, The Netherlands

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  2. B. A. M. Zeijst

    1. State University of Utrecht, Utrecht, The Netherlands

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  3. W. J. M. Spaan

    1. State University of Utrecht, Utrecht, The Netherlands

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  4. M. C. Horzinek

    1. State University of Utrecht, Utrecht, The Netherlands

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 173)

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Table of contents (45 chapters)

  1. Molecular Biology of Coronaviruses

    1. Virus Specific RNAs: Structure and Replication

      1. Glycoprotein E1 of MHV-A59: Structure of the 0-Linked Carbohydrates and Construction of Full Length Recombinant cDNA Clones
        • Heiner Niemann, Gudrun Heisterberg-Moutsis, Rudolf Geyer, Hans-Dieter Klenk, Manfred Wirth
        Pages 201-213
      2. DNA Sequencing Studies of Genomic cDNA Clones of Avian Infectious Bronchitis Virus
        • M. E. G. Boursnell, T. D. K. Brown
        Pages 215-224
      3. The Genome of Transmissible Gastroenteritis Virus (TGEV)
        • Lynne Bountiff, David J. Garwes, Geoffrey C. Millson, G. David Baird
        Pages 225-226

  2. Pathogenesis of Coronaviruses

    1. Overview

      1. Biology of Coronaviruses 1983
        • Volker ter Meulen
        Pages 227-235
      2. MHV-A59 Pathogenesis in Mice
        • Ehud Lavi, Donald H. Gilden, Maureen K. Highkin, Susan R. Weiss
        Pages 237-245
      3. Detection of MHV-A59 RNA by <u>In</u> <u>Situ</u> Hybridization
        • Ehud Lavi, Donald H. Gilden, Maureen K. Highkin, Susan R. Weiss
        Pages 247-257
      4. Virological and Immunological Aspects of Coronavirus Induced Subacute Demyelinating Encephalomyelitis in Rats
        • H. Wedge, R. Watanabe, V. ter Meulen
        Pages 259-270
      5. A One Year Study of Coronavirus SD Infection in Mice
        • L. D. Jankovsky, J. S. Burks, P. Licari, B. L. Devald, M. C. Kemp
        Pages 271-276
      6. Immunosuppression with Cyclophosphamide Does Not Prevent Demyelination or Result in Uncontrolled Viral Replication in Coronavirus SD Infected Mice
        • J. S. Burks, L. Jankovsky, P. A. Licari, I. T. McNally, M. C. Kemp
        Pages 277-278
      7. <u>In</u> <u>Vivo</u> and <u>In</u> <u>Vitro</u> Models of Demyelinating Diseases — VIII: Genetic, Immunologic and Cellular Influences on JHM Virus Infection of Rats
        • O. Sorensen, S. Beushausen, S. Puchalski, S. Cheley, R. Anderson, M. Coulter-Mackie et al.
        Pages 279-298
      8. Restricted Replication of a Temperature Sensitive Mutant of MHV-A59 in Mouse Brain Astrocytes
        • Mario van Berlo, Guus Wolswijk, Jero Calafat, Marian Horzinek, Ben van der Zeijst
        Pages 299-300
      9. Replication of Murine Coronaviruses in Somatic Cell Hybrids Formed Between a Mouse Fibroblast Cell Line and Either a Rat Schwannoma Line or a Rat Glioma Line
        • Wayne F. Flintoff
        Pages 301-313
      10. Persistent <u>In</u> <u>Vitro</u> Infection with Mouse Hepatitis Virus 3
        • Lucie Lamontagne, Jean-Marie Dupuy
        Pages 315-326
      11. Characterization of MHV-A59 Persistently Infected Cells
        • Reinald Repp, Teruko Tamura, Hans-Dieter Klenk, Heiner Niemann
        Pages 327-329
      12. Fine Specificity and Genetic Restriction of T Cell Clones Specific for Mouse Hepatitis Virus, Strain JHM
        • Jerold G. Woodward, John O. Fleming, Glenn K. Matsushima, Jeffrey A. Frelinger, Stephen A. Stohlman
        Pages 331-343
      13. The Immune Response to Mouse Hepatitis Virus: Genetic Variation in Antibody Response and Disease
        • Gary A. Levy, Robert Shaw, Julian L. Leibowitz, Edward Cole
        Pages 345-364
      14. Pathogenic Differences Between Various Feline Coronavirus Isolates
        • Niels C. Pedersen, John W. Black, John F. Boyle, James F. Evermann, Alison J. McKeirnan, Richard L. Ott
        Pages 365-380
      15. Expression of Feline Infectious Peritonitis (FIP) Coronavirus Antigens on the Surface of Feline Macrophage-Like Cells
        • H. E. L. Jacobse-Geels, M. C. Horzinek
        Pages 381-382
      16. Role of Circulating Antibodies and Thymus-Dependent Lymphocytes in Production of Effusive Type Feline Infectious Peritonitis After Oral Infection
        • Toshiharu Hayashi, Kunio Doi, Kosaku Fujiwara
        Pages 383-384
      17. Interactions of Porcine Enteric Coronavirus TGEV with Macrophages and Lymphocytes
        • H. Laude, B. Charley, C. La Bonnardiere
        Pages 385-386
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Keywords

About this book

The present volume contains the Proceedings of an EMBO Workshop organized in June 1983 by the Institute of Virology, Veterinary Faculty, State University of Utrecht, The Netherlands. Some 70 scientists from 11 countries followed the invitation to present and discuss their recent data on the structure, replication, genetics and pathogenesis of coronaviruses. It was the second international meeting on these viruses; the Workshop, which was held in Zeist near Utrecht followed the example of the Wuerzburg symposium of October 1980. At that time it became clear that coronaviruses are unique in many respects. Once a group of viruses that were defined merely on the basis of their characteristic peplomer morphology, Coronaviridae family members are known today - to be constructed from essentially three polypeptides - to use a "nested set" of 5-6 subgenomic mRNAs in the expression of their large, positive and single stranded RNA genome, - to generate these subgenomic RNAs through specific fusion of non­ contiguous sequences, - to mature by budding from intracellular membranes, - to cause persistent infection with neurological involvement and sometimes immunopathological conditons. These and many other findings have been established only very recently. The articles collected in this book reveal and/or further detail these findings. Since these Proceedings contain the combined scientific presentations of representatives from virtually all laboratories engaged in the field, they provide a fairly comprehensive review of the state of the art in corona­ virology.

Editors and Affiliations

  • State University of Utrecht, Utrecht, The Netherlands

    P. J. M. Rottier, B. A. M. Zeijst, W. J. M. Spaan, M. C. Horzinek

Bibliographic Information

  • Book Title: Molecular Biology and Pathogenesis of Coronaviruses

  • Editors: P. J. M. Rottier, B. A. M. Zeijst, W. J. M. Spaan, M. C. Horzinek

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-9373-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1984

  • Softcover ISBN: 978-1-4615-9375-1Published: 25 November 2012

  • eBook ISBN: 978-1-4615-9373-7Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 409

  • Topics: Medical Microbiology

  • Industry Sectors: Biotechnology, Consumer Packaged Goods, Pharma

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