Fertilization Mechanisms in Man and Mammals

  • Ralph B. L. Gwatkin

Table of contents

  1. Front Matter
    Pages i-x
  2. Ralph B. L. Gwatkin
    Pages 1-3
  3. Ralph B. L. Gwatkin
    Pages 5-12
  4. Ralph B. L. Gwatkin
    Pages 13-25
  5. Ralph B. L. Gwatkin
    Pages 27-32
  6. Ralph B. L. Gwatkin
    Pages 33-51
  7. Ralph B. L. Gwatkin
    Pages 53-60
  8. Ralph B. L. Gwatkin
    Pages 61-67
  9. Ralph B. L. Gwatkin
    Pages 81-85
  10. Ralph B. L. Gwatkin
    Pages 87-89
  11. Ralph B. L. Gwatkin
    Pages 91-102
  12. Ralph B. L. Gwatkin
    Pages 103-108
  13. Ralph B. L. Gwatkin
    Pages 109-112
  14. Ralph B. L. Gwatkin
    Pages 115-119
  15. Ralph B. L. Gwatkin
    Pages 121-124
  16. Back Matter
    Pages 125-161

About this book


Fertilization in mammals normally occUrs within the oviduct, where it is relatively inaccessible to study. However, as a result of painstaking research, most of it carried out over the last five years, this barrier to experimentation has been largely overcome by the development of in vitro fertilization techniques for at least 11 different species, including man. The result has been a rapid increase in our knowledge of the physiological and bio­ chemical mechanisms involved in the fertilization process. The aim of this book, which is an extension of my recent review of cell surface interactions in fertilization (Gwatkin, 1976), is to present a brief, but well documented, account of the new knowledge that has been attained. Although this book deals with mammalian fertilization mechanisms, I have included some recent experiments on am­ phibian and invertebrate gametes to supplement the mammalian picture. This information is particularly valuable as the rela­ tively large number of eggs available from these lower forms has advanced our knowledge of certain fertilization mechanisms beyond what is known in mammals. However, in the interest of brevity, I have omitted details of morphology and minor varia­ tions between species. For these, and other aspects not covered here, the reader is referred to the books of Austin (1965, 1968), vii viii PREFACE Austin and Short (1972), Metz and Monroy (1969), Monroy (1965), Lord Rothschild (1956a), and Zamboni (l971a).


cell development experiment fertilization information invertebrates mammals morphology

Authors and affiliations

  • Ralph B. L. Gwatkin
    • 1
  1. 1.Merck Institute for Therapeutic ResearchRahwayUSA

Bibliographic information