Placental Vascularization and Blood Flow

Basic Research and Clinical Applications

  • Peter Kaufmann
  • Richard K. Miller

Part of the Trophoblast Research book series (TR, volume 3)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Maternal Circulation

  3. Fetal Circulation

    1. Front Matter
      Pages 111-111
    2. Peter Kaufmann, Michael Luckhardt, Rudolf Leiser
      Pages 113-137
    3. Bae-Li Hsi, Chang-Jing G. Yeh
      Pages 139-148
    4. Dirk Heinrich, Augustin Aoki, Jürgen Metz
      Pages 149-162
    5. J. Anthony Firth, Karol F. Bauman, Colin P. Sibley
      Pages 163-177
    6. Debra F. Anderson, J. Job Faber
      Pages 179-188
  4. Maternal/Fetal Interrelations

    1. Front Matter
      Pages 215-215
    2. Elizabeth M. Ramsey, Martin W. Donner
      Pages 217-233
    3. Vibeke Dantzer, Rudolf Leiser, Peter Kaufmann, Michael Luckhardt
      Pages 235-260
  5. Diagnostic Methods

    1. Front Matter
      Pages 269-269
    2. Dev Maulik, Prasad Yarlagadda
      Pages 283-289
  6. Clinical Applications

    1. Front Matter
      Pages 291-291
    2. Dev Maulik, Prasad Yarlagadda, Lee Willoughby
      Pages 293-300
    3. Isabel Stabile, Caterina Bilardo, Marco Panella, Stuart Campbell, J. Gedis Grudzinskas
      Pages 301-307
    4. Catherine Nessmann, Yolene Huten, Michele Uzan
      Pages 309-323
    5. Moira R. Jackson, Terry M. Mayhew, Jere D. Haas
      Pages 351-360
  7. Back Matter
    Pages 361-370

About this book


The optimal function of the placenta and thus fetal well being largely depends upon the integrity of both the fetal and maternal circulations of the placenta. Intense basic research concerned with placental vascularization and blood flow has been performed for the past 30 years, beginning with the classical morphological descriptions of the placental vessels by Boe (1953) and Arts (1961), as well as with the radioangiographic studies of maternal placental circulation in the human by Borell (1958) and in the rhesus monkey by Ramsey (1962). The scientific framework presented by these investigators has been filled and completed by numerous investigators, leading to more morphological details, functional considerations, and pathological understanding. For an extended period of time, this research has been of primarily academic interest by increasing our insights into one important system of the placenta, yet having nearly no practical importance. Recently, this situation has changed dramatically: in vitro studies of the isolated, dually perfused human placenta and in vivo studies of placental circulation for diagnostic purposes have raised an enormous interest in basic research data. New methods like Doppler Ultrasound and NMR became available. These technics have enabled the obstetrician to study fetal and placental hemodynamics in vivo. Meanwhile, such methods are becoming incorporated into the daily obstetrical routine, to some degree without an adequate background knowledge of placental vascularization and blood flow, since such experience is currently available to only a small group of experts.


NMR blood circulation dynamics hemodynamics nuclear magnetic resonance (NMR) placenta pregnancy regulation research ultrasound

Editors and affiliations

  • Peter Kaufmann
    • 1
  • Richard K. Miller
    • 2
  1. 1.RWTH AachenAachenFederal Republic of Germany
  2. 2.University of Rochester Medical CenterRochesterUSA

Bibliographic information

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