Handbook of Genetics

Volume 5: Molecular Genetics

  • Robert C. King

Table of contents

  1. Front Matter
    Pages i-xi
  2. The Molecular Organization of Chromosomes

    1. Front Matter
      Pages 1-1
    2. Neil A. Straus
      Pages 3-29
    3. Ronald A. Eckhardt
      Pages 31-53
    4. Ru Chih C. Huang, Rex P. Hjelm Jr.
      Pages 55-111
    5. David P. Bloch
      Pages 139-167
    6. Robert B. Painter
      Pages 169-186
  3. Gene Transcripts

    1. Front Matter
      Pages 187-187
    2. Bertil Daneholt
      Pages 189-217
    3. Anton J. M. Berns, Hans Bloemendal
      Pages 267-303
    4. James T. Madison
      Pages 305-323
    5. Mary G. Hamilton
      Pages 325-367
  4. Chloroplasts and Mitochondria

    1. Front Matter
      Pages 369-369
    2. Ruth Sager, Gladys Schlanger
      Pages 371-423
    3. Erhard Stutz, Arminio Boschetti
      Pages 425-450
    4. Hans-Georg Schweiger
      Pages 451-475
    5. Margit M. K. Nass
      Pages 477-533
    6. Thomas W. O’Brien, David E. Matthews
      Pages 535-580
  5. Mutant Enzymes

    1. Front Matter
      Pages 581-581
    2. Charles R. Shaw, Rupi Prasad
      Pages 583-616
  6. Errata for Previous Volumes

    1. Robert C. King
      Pages 617-618
  7. Back Matter
    Pages 619-667

About this book


Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech­ niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func­ tioning of the molecules bearing genetic information which reside in the nucleus and with the processing of this information by the ribosomes resid­ ing in the cytoplasm of eukaryotic cells. The mitochondria, which also live in the cytoplasm of the cells of all eukaryotes, now appear to be separate little creatures. These, as Lynn Margulis pointed out in Volume 1, are the colonial posterity of migrant prokaryotes, probably primitive bacteria that swam into the ancestral precursors of all eukaryotic cells and remained as symbionts. They have maintained themselves and their ways ever since, replicating their own DNA and transcribing an RNA quite different from that of their hosts. In a similar manner, the chloroplasts in all plants are self-replicating organelles presumably derived from the blue-green algae, with their own nucleic acids and ribosomes. Four chapters are devoted to the nucleic acids and the ribosomal components of both classes of these semi-independent lodgers. Finally, data from various sources on genetic variants of enzymes are tabulated for ready reference, and an evaluation of this information is attempted.


DNA Organelle chromosome genes genetics transcription

Editors and affiliations

  • Robert C. King
    • 1
  1. 1.Department of Biological SciencesNorthwestern UniversityEvanstonUSA

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