The Fate of the Male Germ Cell

  • Richard Ivell
  • Adolf-Friedrich Holstein

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 424)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Human Reproduction

    1. B. P. Setchell
      Pages 1-15
  3. Genes,Chromosomes,and Fertility

    1. A. Bonhoff, R. Fischer, V. Baukloh, O. G. J. Naether, W. Schulze, W. Höppner
      Pages 31-35
    2. D. Doenecke, B. Drabent, C. Bode, B. Bramlage, K. Franke, K. Gavénis et al.
      Pages 37-48
    3. O. Witt, K. Gavénis, D. Doenecke
      Pages 49-50
  4. Germ Cell Differentiation and Tumorigenesis

    1. G. F. Weinbauer, E. Nieschlag
      Pages 51-58
    2. A. Meinhardt, H. Renneberg, A. Dersch, G. Wennemuth, J. L. Millán, G. Aumüller et al.
      Pages 61-63
    3. W. Pusch, M. Balvers, N. Hunt, R. Ivell
      Pages 65-66
    4. H. Lauke
      Pages 69-70
    5. D. Benson, H. Lauke, M. Hartmann
      Pages 71-72
    6. M. Mueller, H. Lauke
      Pages 73-74
    7. T. Böhmer, T. Pottek, H. Büttner, M. Hartmann
      Pages 75-76
    8. K. H. Schölermann, H. Lauke, H. Huland, M. Hartmann
      Pages 77-78
    9. T. Pottek, H. Lauke, M. Hartmann
      Pages 79-80
    10. W. Schulze, U. A. Knuth, D. Jezek, D. M. Benson, R. Fischer, O. G. J. Naether et al.
      Pages 81-88
  5. The Role of the Testicular Accessory Cells

    1. M. Simoni, J. Gromoll, W. Höppner, E. Nieschlag
      Pages 89-97
    2. P. T. K. Saunders, G. Majdic, P. Parte, M. R. Millar, J. S. Fisher, K. J. Turner et al.
      Pages 99-110
    3. T. K. Monsees, W. B. Schill, W. Miska
      Pages 111-123
    4. R. Middendorff, D. Müller, H. J. Paust, A. F. Holstein, M. S. Davidoff
      Pages 125-138
    5. N. Walther, M. Jansen, S. Ergün, B. Kascheike, G. Tillmann, R. Ivell
      Pages 139-142
    6. S. G. Haider, G. Servos, S. Tajtaraghi, G. Berthold, A. K. Mukhopadhyay, N. Kilic et al.
      Pages 143-144
    7. C. Hansis, D. Jähner, A.-N. Spiess, R. Ivell
      Pages 147-149
    8. M. S. Davidoff, R. Middendorff, D. Müller, E. Köfüncü, A. F. Holstein
      Pages 151-152
    9. B. Drescher, W. Zumkeller, H. Lauke, M. Hartmann, M. S. Davidoff
      Pages 153-154
    10. D. Müller, R. Middendorff
      Pages 155-156
    11. D. Müller, H.-J. Paust, R. Middendorff, M. S. Davidoff
      Pages 157-158
  6. Compartmentalization, Vascularization, and Angiogenesis

    1. A. F. Holstein, M. Davidoff
      Pages 161-162
    2. S. Ergün, N. Kilic, S. Harneit, H. J. Paust, H. Ungefroren, A. Mukhopadhyay et al.
      Pages 163-180
    3. S. Ergün, T. Bruns, R. Tauber
      Pages 183-184
    4. T. Bruns, R. Tauber, S. Ergün
      Pages 185-186
    5. S. Ergün, W. Empen, W. Fiedler
      Pages 189-190
    6. S. Harneit, S. Ergün, A. F. Holstein, H.-J. Paust, A. K. Mukhopadhyay
      Pages 191-192
  7. Post-Testicular Sperm Maturation

    1. G. Aumüller, H. Renneberg, P.-J. Schiemann, B. Wilhelm, J. Seitz, L. Konrad et al.
      Pages 193-219
    2. C. Kirchhoff, I. Pera, P. Derr, C.-H. Yeung, T. Cooper
      Pages 221-232
    3. S. Schröter, C. Kirchhoff, C.-H. Yeung, T. Cooper, B. Meyer
      Pages 233-234
    4. G. Wennemuth, S. Eisoldt, H. P. Bode, H. Renneberg, G. Aumüller
      Pages 235-237
    5. P. Baltes, R. Sánchez, R. Henkel, W. Miska
      Pages 239-240
    6. W. Miska, U. K. Schalles, J. Villegas, R. Henkel
      Pages 241-242
  8. Control of the Male and Female Tracts

    1. R. Ivell, M. Balvers, W. Rust, R. Bathgate, A. Einspanier
      Pages 253-264
    2. Z. Halata, A. Spaethe
      Pages 265-266
    3. G. Kunz, D. Beil, Н. Deiniger, A. Einspanier, G. Mall, G. Leyendecker
      Pages 267-277

About this book


THE FASCINATION The male germ cell is the only cell of the human organism that leaves the body when it has achieved its final, highly sophisticated structure and properties. The male germ cell is designed for one purpose only: to reach the female gametes and to fertilize them. The various stages in the development of the male germ cell are characterized by proliferative phases, by the recombination of the maternal and paternal chromosomes, and by the differentiation and development of a specialized transport vehicle, the spermato­ zoon. Furthermore, the establishment of a special pool of stem cells, the spermatogonia, guarantees the continuity of the sperm-generation process from puberty to old age. THE FATE OF THE MALE GERM CELL The destiny of any individual germ cell is determined by a program that we know only in fragments. On the one hand every human male is able to produce many billions of germ cells in his lifetime, yet the chance of any single sperm reaching and fertilizing the female germ cell is exceedingly rare. A fertility disturbance means that somewhere during the complicated playing out of the germ cell program mistakes are made, and the program fails. It is still a fact that more than 50% of men presenting with male factor infertility have to be diagnosed as idiopathic, largely because of our lack of knowledge and conse­ quent lack of appropriate diagnostic tools.


Chromosom Tumor biology chromosome development diagnosis physiology recombination

Editors and affiliations

  • Richard Ivell
    • 1
  • Adolf-Friedrich Holstein
    • 2
  1. 1.Institute for Hormone and Fertility ResearchUniversity of HamburgHamburgGermany
  2. 2.Anatomical InstituteUniversity of HamburgHamburgGermany

Bibliographic information

  • DOI
  • Copyright Information Plenum Press, New York 1997
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7711-5
  • Online ISBN 978-1-4615-5913-9
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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