Gene Therapy of Cancer

1. Chemogene Therapy

   1. Potentiation of the Bystander Effect by Immunization Combined With Suicide Gene Therapy

      • Rajagopal Ramesh, Aizen J. Marrogi, Anupama Munshi, Scott M. Freeman

      Pages 125-131

   2. Another Mechanism Causing the Bystander Effect Besides the GAP Junction’s Role During the Glioma Gene Therapy With HSV-TK/GCV System

      • Liping Du, Shaochun Bai, Ian R. Whittle, Lin He

      Pages 133-138

   3. In Vivo Evaluation of a Drug-Inducible Vector System for the Combined Gene-and Chemotherapy of Cancer

      • Wolfgang Walther, U. Stein, I. Fichtner, H. Naundorf, M. Alexander, R. H. Shoemaker et al.

      Pages 139-144

   4. IL-2 Gene Transfer for Chemosensitization of Multidrug-Resistant Human Colon Carcinoma Cells

      • Ulrike Stein, Wolfgang Walther, Robert H. Shoemaker, Peter M. Schlag

      Pages 145-149

   5. Cytotoxic Effect of Binar Cisplatin Immunoconjugate

      • V. M. Plotnikov

      Pages 151-152

   6. Dietary Indole Derivatives Induce Apoptosis in Human Breast Cancer Cells

      • Fuad A. Fares, Xiaokang Ge, Shmuel Yannai, Gad Rennert

      Pages 153-157

2. Tumor Immunology

   1. Overcoming T Cell Ignorance by Providing Costimulation

      • Lieping Chen

      Pages 159-165

   2. Immune Cells in the Tumor Microenvironment

      • Theresa L. Whiteside

      Pages 167-171

   3. Dendritic Cells Prevent CD95 Mediated T Lymphocyte Death through Costimulatory Signals

      • Peter T. Daniel, C. Scholz, J. Westermann, B. Dörken, A. Pezzutto

      Pages 173-177

   4. Interleukin-10 Inhibits the Immune Stimulatory Potential of Melanoma Cells Retrovirally Transduced with Human B7.1 or B7.2

      • Ralf Geertsen, F.-Y. Yue, J. Pavlovic, E. Laine, R. Dummer

      Pages 179-188

   5. Immunosuppressive Cells in Bone Marrow of Patients with Stomach Cancer

      • Sergei A. Kusmartsev, I. N. Kusmartseva, S. G. Afanasyev, N. V. Cherdyntseva

      Pages 189-194

   6. Induction of Antigen-Specific T Cells by Allogeneic CD80 Transfected Human Carcinoma Cells

      • G. C. Meyer, U. Moebius, W. Rudy, R. Batrla, S. C. Meuer, D. Wallwiener et al.

      Pages 195-202

   7. IL-12-Activated NK Cells Recognize B7 Costimulatory Molecules on Tumor Cells and Autologous Dendritic Cells

      • Anja B. Geldhof, M. Moser, P. De Baetselier

      Pages 203-210

   8. Effects of Altered Antigen Processing on T-Cell Responses Toward Murine T-Lymphomas

      • Geert Raes, J. Van Ginderachter, N. Devoogdt, A. Geldhof, P. De Baetselier

      Pages 211-215

   9. Cancer Gene Therapy with a Heat Shock Protein Gene

      • O. E. Pardo, J. M. Colston, Katalin V. Lukacs

      Pages 217-223

   10. Heat Shock Protein (HSP72) Surface Expression Enhances the Lysis of a Human Renal Cell Carcinoma by IL-2 Stimulated NK Cells

       • Jan Roigas, E. S. Wallen, S. A. Loening, P. L. Moseley

       Pages 225-229

   11. Identification of Epitopes for CTCL-Specific Cytotoxic T Lymphocytes

       • Thomas Linnemann, Carsten Brock, Katrin Sparbier, Marcus Muche, Arlett Mielke, Ansgar Lukowsky et al.

       Pages 231-235

   12. Effects of Altered Antigen Processing on H-2Dk Mediated NK Inhibition in a Murine T Lymphoma Model

       • J. Van Ginderachter, G. Raes, N. Devoogdt, P. De Baetselier, A. Geldhof

       Pages 237-240

   13. Recognition of Melanoma-Associated Peptides by Peripheral Blood Mononuclear Cells of Ocular Melanoma Patients

       • J. Saba, C. A. McIntyre, R. C. Rees, A. K. Murray

       Pages 241-244

   14. Detection of Micrometastasis in 31 Patients with Breast Cancer by RT-PCR and Immunomagnetic Separation (ISM) Techniques

       • Ramiro Cevallos, M. Del Pozo, D. Zylberait, P. Naepels, P. Veyssier, L. Geffray et al.

       Pages 245-246

The book provides a comprehensive overview of the current state, and the new concepts for the future directions of modern cancer therapy. Bringing together all the relevant aspects from basic and applied science, and the clinical experiences of this new direction in medicine, it is an up-to-date summary of the activities in the field and will be the basis for evaluating future progress in this area.

• Herpes simplex
• Peptide
• angiogenesis
• apoptosis
• bone
• carcinoma
• endothelium
• tissue
• tumor growth
• tumorigenesis

• Humboldt University, Berlin, Germany

  Peter Walden, Uwe Trefzer, Wolfram Sterry, Patricia Zambon

• King’s College School of Medicine and Dentistry, London, UK

  Farzin Farzaneh

Policies and ethics