Intracellular Cholesterol Trafficking

  • T. Y. Chang
  • Dale A. Freeman

Table of contents

  1. Front Matter
    Pages i-x
  2. Regulation of ACAT and Intracellular Cholesterol Level

    1. Ta-Yuan Chang, Catherine C. Y. Chang, Oneil Lee
      Pages 1-14
    2. Robert V. Farese Jr., Sylvaine Cases, Sabine Novak
      Pages 29-42
    3. Peter Oelkers, Stephen L. Sturley, Arthur Tinkelenberg
      Pages 43-51
  3. Niemann-Pick Type C Disease

  4. Cholesterol Transport in Specialized Cells

    1. Yong-Soon Choi, Dale A. Freeman
      Pages 109-121
    2. F. Jeffrey Field
      Pages 123-145
    3. Jane Ellen Phillips, William J. Johnson
      Pages 147-168
    4. Douglas M. Stocco, Jerome F. Strauss III
      Pages 169-182
  5. Sterol Carrier Protein-2 and Cholesterol Transport Proteins

    1. R. F. Chanderbhan, A. T. Kharroubi, A. P. Pastuszyn, L. L. Gallo, T. J. Scallen
      Pages 197-212
    2. Friedhelm Schroeder, Andrey Frolov, Jonathan K. Schoer, Adalberto M. Gallegos, Barbara P. Atshaves, Neal J. Stolowich et al.
      Pages 213-234
  6. Caveolae and Caveolin

    1. Eric J. Smart, Deneys R. van der Westhuyzen
      Pages 253-272
    2. Christopher J. Fielding, Anita Bist, Phoebe E. Fielding
      Pages 273-288
  7. Summary and Future Perspectives

    1. Ta-Yuan Chang
      Pages 289-292
  8. Back Matter
    Pages 293-294

About this book


INTRODUCTION AND RATIONALE FOR INTRACELLULAR CHOLESTEROL TRAFFICKING This volume is an elaboration of an earlier small meeting held in St. Louis, Missouri. In April 1997, many of the authors met for a two-day meeting devoted entirely to intracellular cholesterol trafficking. The rationale for this meeting was that investigators interested in this topic worked in a variety of fields, and rarely, if ever, all met together. Everybody knew each other's papers but mostly worked in isolation from one another. Understanding of cholesterol trafficking also appeared to have reached the point where it would start to rapidly expand beyond these few laboratories. Understanding of cholesterol trafficking was moving from a largely descriptive science into the molecular age. It seemed a good time to get together and see how much we agreed upon up to this point. More authors contributed to this volume than attended the St. Louis meeting. That meeting was generously funded by grants from Bristol-Myers Squibb, Merck and Company and Parke-Davis, however, the total funding available limited the size of the meeting. For the book, we are not so limited and have tried to be as inclusive as possible and pretty much invited everyone who is presently active in this area. We were quite fortunate to successfully recruit the authors we sought for each of these chapters. The authors and their contributions can be organized by particular interests and particular areas of expertise.


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Editors and affiliations

  • T. Y. Chang
    • 1
  • Dale A. Freeman
    • 2
  1. 1.Dartmouth Medical SchoolUSA
  2. 2.University of Oklahoma Health Sciences CenterUSA

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