The Functional Roles of Glial Cells in Health and Disease

Dialogue between Glia and Neurons

  • Rebecca Matsas
  • Marco Tsacopoulos

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 468)

Table of contents

  1. Front Matter
    Pages i-x
  2. Glial Cell Development

    1. Front Matter
      Pages 1-1
    2. K. R. Jessen, R. Mirsky
      Pages 3-12
    3. Wim Mandemakers, Ronald Zwart, Robert Kraay, Gerard Grosveld, Anneke Graus Martine Jaegle, Ludo Broos et al.
      Pages 13-22
    4. Christian Klämbt, Kristina Schimmelpfeng, Thomas Hummel
      Pages 23-32
    5. A. A. Miller, R. Bernardoni, C. Hindelang, M. Kammerer, S. Sorrentino, V. Van de Bor et al.
      Pages 33-46
  3. Glia In Neurotransmission, Neuromodulation, and Neuron Survival

    1. Front Matter
      Pages 47-47
    2. Daniele F. Condorelli, Fiorenzo Conti, Vittorio Gallo, Frank Kirchhoff, Gerald Seifert, Christian Steinhäuser et al.
      Pages 49-67
    3. Paola Bezzi, Sabino Vesce, Patrizia Panzarasa, Andrea Volterra
      Pages 69-80
    4. Thomas Rauen, Frauke Fischer, Michael Wiessner
      Pages 81-95
    5. Carlos Matute, María Domercq, David J. Fogarty, María Pascual de Zulueta, María Victoria Sánchez-Gómez
      Pages 98-107
    6. Luisa Minghetti, Elisabetta Polazzi, Alessia Nicolini, Anita Greco, Giulio Levi
      Pages 109-119
  4. Glia, Inflammation, and Cytokines

    1. Front Matter
      Pages 121-121
    2. N. Woodroofe, A. K. Cross, K. Harkness, J. E. Simpson
      Pages 135-150
    3. Gisela Wohlleben, Hans-Peter Hartung, Ralf Gold
      Pages 151-156
    4. B. Finsen, N. D. Lomholt, I. V. Hegelund, F. R. Poulsen, M. B. Jensen, T. Owens
      Pages 157-171
  5. Glia in cns Plasticity and Regeneration

    1. Front Matter
      Pages 173-173
    2. Dionysia T. Theodosis, Dominique A. Poulain
      Pages 175-182
    3. Hans S. Keirstead, William F. Blakemore
      Pages 183-197
    4. Manuel Nieto-Sampedro
      Pages 207-224
  6. Transgenic Models of Human Myelin Diseases

    1. Front Matter
      Pages 225-225
    2. Dirk H. H. Neuberg, Ueli Suter
      Pages 227-236
    3. Brian Popko, Jeffrey L. Dupree, Timothy Coetzee, Kinuko Suzuki, Kunihiko Suzuki
      Pages 237-244
    4. Katerina Akassoglou, George Kassiotis, George Kollias, Lesley Probert, Jan Bauer, Hans Lassmann
      Pages 245-259
    5. L. Dimou, M. Klugmann, H. Werner, M. Jung, K.-A. Nave, I. R. Griffiths
      Pages 261-271
  7. Neuron-glial Communication: Neurotrophins and Cell Adhesion Molecules

    1. Front Matter
      Pages 273-273
    2. P. Casaccia-Bonnefil, C. Gu, M. V. Chao
      Pages 275-282
    3. Mark A. Marchionni, Carolyn Hoban, Renee Garcia-Arenas, Deborah Lawson, Elizebeth Happel, David Gwynne et al.
      Pages 283-295
    4. Susan C. Barnett, Isabelle A. Franceschini
      Pages 297-307
    5. Jean-Michel Revest, Catherine Faivre-Sarrailh, Geneviève Rougon, Melitta Schachner
      Pages 309-318
  8. Connexins and Information Transfer Through Glia

    1. Front Matter
      Pages 319-319
    2. Roberto Bruzzone, Christian Giaume
      Pages 321-337
    3. David C. Spray, Heather S. Duffy, Eliana Scemes
      Pages 339-359
    4. José M. Medina, Arantxa Tabernero, Christian Giaume
      Pages 361-371
    5. Christian C. G. Naus, Mahmud Bani-Yaghoub, John F. Bechberger, Walter Rushlow
      Pages 373-381

About this book


Thirty-five years ago, when Stephen Kuffler and his colleagues at Harvard initiated a new era of research on the properties and functions of neuroglial cells, very few neuro­ scientists were impressed at the time with the hypothesis that neuroglial cells could have another, though more subtle, role to play in the nervous system than to provide static support to neurons. Today, very few neuroscientists are unaware of the fact that multiple interactions between neurons and glial cells have been described, and that they consti­ tute the basis for understanding the function and the pathology of the nervous system. Glial cells outnumber neurons and make up about one-half of the bulk of the nervous system. They are divided into two major classes: first, the macroglia, which include astrocytes and oligodendrocytes in the central nervous system, and the Schwann cells in the peripheral nervous system; and second, the microglial cells. These different classes of glial cells have different functions and contribute in different ways in the devel­ opment, function, and the pathology of the nervous system.


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Editors and affiliations

  • Rebecca Matsas
    • 2
  • Marco Tsacopoulos
    • 1
  1. 1.University of Geneva Medical SchoolGenevaSwitzerland
  2. 2.Hellenic Pasteur InstituteAthensGreece

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 1999
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-7121-2
  • Online ISBN 978-1-4615-4685-6
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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