Advances in haemapheresis

1. Stem Cells: Clinical Application

   1. Peripheral Blood Stem Cell Transplants in Myeloma

      • T. J. Hamblin, A. J. Bell, R. Cusak, A. Figes, J. North, F. K. Stevenson

      Pages 133-138

   2. High Dose Chemotherapy and Blood Stem Cell Autologous Graft in Multiple Myeloma

      • J. P. Fermand, Y. Levy, M. Adam, X. Sithy, J. M. Miclea, S. Chevret et al.

      Pages 139-144

   3. Stem Cell Harvesting from Umbilical Cord Blood: A New Perspective

      • E. Gluckman, D. Thierry, Y. Brossard, M. Benbunan, Y. Gerotta, A. Auerbach et al.

      Pages 145-151

   4. Circulating Stem Cells for Autografting: A Perspective for Hematopoietic Growth Factors

      • H. H. Gerhartz

      Pages 153-157

2. In Vivo Versus in Vitro Modulation of Lymphocytes

   1. Front Matter

      Pages N4-N4

      PDF

   2. In Vivo Versus Ex Vivo Modulation of Lymphocytes; Immunotherapy for Hematological Malignancies

      • D. van der Harst, A. Brand, J. J. van Rood

      Pages 159-164

   3. The Promise of T Cell Immunotherapy of Cancer

      • C. J. M. Melief, W. M. Kast

      Pages 165-172

   4. Photopheresis: A New Approach to the Management of T-Cell Mediated Disorders

      • R. Edelson

      Pages 173-187

   5. High Levels of Circulating Hematopoietic Progenitor Cells after Continuous Infusion of High Dose Interleukin-2 in Cancer Patients

      • M. R. Schaafsma, J. H. F. Falkenburg, N. Duinkerken, D. van der Harst, A. Brand, S. Osanto et al.

      Pages 189-196

3. Single Versus Multiple Donor Platelets

   1. Front Matter

      Pages N5-N5

      PDF

   2. Is Leukocyte Depletion Important in the Prevention of Alloimmunization by Random Single Donor Platelet Transfusion?

      • J. Gmür, U. Schanz, J. Burger, M. Reichlin, E. Müller, O. Oelz

      Pages 197-203

   3. UV Irradiation: Effects on the Immune System and on Platelet Function, Viability, and Alloimmunization

      • S. J. Slichter

      Pages 205-228

   4. Purification of Platelet Concentrates by Elutriation: Elutriated Single Versus Pooled Multiple Donor Platelets

      • M. K. Elias, L. Rijskamp, M. Weggemans, R. L. McShine, J. W. Smit, J. Pietens et al.

      Pages 229-243

   5. Platelet Concentrates from Buffy Coats

      • F. Bertolini, P. Rebulla, D. Riccardi, L. Porretti, C. Smacchia, S. Murphy et al.

      Pages 245-254

   6. Selection of Platelet Apheresis Donors for Alloimmunized Patients by ELISA Platelet Crossmatch Versus HLA-Matching

      • K. Sintnicolaas, J. Priem, W. Sizoo, R. L. H. Bolhuis

      Pages 255-261

4. Back Matter

   Pages 263-270

   PDF

The first International Meeting on Apheresis was held in Dyon in 1984. At the congress it became clear that both the technical and therapeutic sides developed very rapidly and it appeared fruitful to bring together the investigators of the different countries working in the areas. At that time immunology had come to pervade many clinical specialities, and hemapheresis, especially plasmapheresis was considered a therapeutic tool in many immunological diseases which hitherto had proved to be fatal. New methods to identify certain antibodies and circulating immune complexes in the serum and the possibilities to remove them from the blood by several techniques (filtration, centrifugation, immunoabsorp­ tion) led to an almost uncontrolled use of plasma exchange in a variety of diseases. Since then the technical possibilities of this technique were further recognized, as was the impact of immunology on many diseases, and the possibilities to collect specific components for therapeutic pur­ poses. But also we became aware of the limited contributions of anec­ dotal data on successes or failures of apheresis as adjuvant treatment. Therefore international prospective studies were initiated to make critical assessment possible of apheresis in various diseases.

• T cell
• blood
• bone marrow
• chemotherapy
• diseases
• immune system
• immunoglobulin
• immunology
• immunotherapy
• lymphocytes
• neurology
• plasma
• prevention
• stem cells
• transplantation

• Red Cross Blood Bank Groningen-Drenthe, The Netherlands

  C. Th. Smit Sibinga

• University Hospital Utrecht, The Netherlands

  L. Kater

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