Formation and Differentiation of Early Embryonic Mesoderm

  • Ruth Bellairs
  • Esmond J. Sanders
  • James W. Lash

Part of the NATO ASI Series book series (NSSA, volume 231)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Kirstie A. Lawson, Roger A. Pedersen
    Pages 33-46
  3. Roswitha Seifert, Heinz Jürgen Jacob, Monika Jacob
    Pages 63-76
  4. Monika Jacob, Heinz Jürgen Jacob, Roswitha Seifert
    Pages 77-86
  5. Charles ffrench-Constant, Richard O. Hynes, Janet Heasman, Christopher C. Wylie
    Pages 99-108
  6. Sara E. Zalik, Eliane Didier, Irene M. Ledsham, Esmond J. Sanders, Christopher K. Guay
    Pages 109-118
  7. Antone G. Jacobson
    Pages 119-131
  8. James W. Lash, Dukhee Rhee, Joseph T. Zibrida, Nancy Philp
    Pages 169-180
  9. Geoffrey M. W. Cook, Roger J. Keynes
    Pages 181-191
  10. Sarah E. Herrick, Heather Taylor, Grenham W. Ireland
    Pages 227-240
  11. Ruth Bellairs, Heather Easton, P. Govewalla, G. D. Harrison, M. Y. Palmer, R. C. Pollock et al.
    Pages 263-273
  12. Jörg Wilting, Bodo Christ, Milos Grim, Pascale Wilms
    Pages 315-322
  13. Ingo Flamme, Marius Messerli, Werner Risau, Monika Jacob, Heinz Jürgen Jacob
    Pages 323-335
  14. Back Matter
    Pages 337-341

About this book


Mesodenn is a key tissue in early development. It is involved in the differentiation of almost every organ in the body, not merely as a structural component, but as an active participant in the establishment of diverse cell types. All mesodenn is derived from ectoderm. Its appearance signals the start of a significant new phase in the development of the embryo. At this time all three genn layers are now present and myriad sequences of cell and tissue interactions begin to occur which will eventually give rise to the entire embryo. The control of the growth and differentiation of the mesoderm is critical for the production of a normal individual. Indeed, disturbance of the patterning of the mesoderm or of its interaction with other tissues plays a critical part in the fonnation of most congenital anomalies. The main focus of this book is therefore on the establishment, divergence and specialisation of mesodermal derivatives. The central role of the mesoderm in development has long been appreciated and a wide literature exists on its activity in certain specialised situations. Recently, however, an impetus to its study has been provided by new approaches opened up through biotechnological advances. Many of these advances are reflected in the reports in this volume. Scientists from various disciplines have become drawn to mesodermal tissues, and this volume may help them find a framework within which their work will fit.


Embryo Mesoderm Vertebrate development tissue

Editors and affiliations

  • Ruth Bellairs
    • 1
  • Esmond J. Sanders
    • 2
  • James W. Lash
    • 3
  1. 1.University College LondonLondonUK
  2. 2.University of AlbertaEdmontonCanada
  3. 3.University of PennsylvaniaPhiladelphiaUSA

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