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Multidisciplinary Treatment of Soft Tissue Sarcomas

  • Jaap Verweij
  • Herbert M. Pinedo
  • Herman D. Suit

Part of the Cancer Treatment and Research book series (CTAR, volume 67)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Jonathan A. Fletcher
    Pages 23-35
  3. Colin S. Cooper, Jeremy Clark
    Pages 37-55
  4. Kristian Herrlin, Holger Pettersson
    Pages 57-79
  5. Dempsey S. Springfield
    Pages 81-98
  6. Wilson C. Mertens, Vivien H.C. Bramwell
    Pages 117-133
  7. C. Jay Engel, Frederick R. Eilber, Gerald Rosen, Michael T. Selch, Yao-Shi Fu
    Pages 135-141
  8. Rolf D. Issels
    Pages 143-160
  9. Charles B. Pratt, Larry E. Kun
    Pages 161-182
  10. Back Matter
    Pages 183-191

About this book

Introduction

The previous volume of this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, the focus of which is continued in the present edition. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology techniques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of the prognosis of the patient as well as providing data for the planning of treatment strategy. The use of cytogenetics is relatively new in this field. This might enable the distinction of subgroups in specific histological tumor types. Furthermore, molecular biological studies not only help to reveal inherited predispositions and details in oncogenesis in tumor development, but they may also provide additional predictive factors for tumor behavior. Further data on treatment strategy will be provided by diagnostic imaging, a field in which the role of magnetic resonance imaging is rapidly developing. As far as actual treatment is concerned, surgery still provides the major chance for cure. In view of the endeavor to be as sparing as possible, the addition of radiotherapy to surgery is of utmost importance. Usually radiotherapy is given after surgery, but the optimal sequence of the two modalities still needs to be defined. The combined use of surgery with radiotherapy and/or chemotherapy does have an impact on wound healing.

Keywords

Grading Staging histopathology imaging metastatic disease surgery

Editors and affiliations

  • Jaap Verweij
    • 1
  • Herbert M. Pinedo
    • 2
  • Herman D. Suit
    • 3
  1. 1.Department of Medical OncologyRotterdam Cancer InstituteRotterdamThe Netherlands
  2. 2.Department of Medical OncologyFree University HospitalAmsterdamThe Netherlands
  3. 3.Department of Radiation Medicine Massachusetts General HospitalHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-3082-4
  • Copyright Information Kluwer Academic Publishers 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6346-0
  • Online ISBN 978-1-4615-3082-4
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site
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