Molecular Biology and Virus-Host Interactions

  • Hubert Laude
  • Jean-François Vautherot

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 342)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Coronavirus Genes: Comparative Aspects

    1. Front Matter
      Pages 1-1
    2. Brian C. Horsburgh, T. David K. Brown
      Pages 3-9
    3. H. Vennema, J. W. A. Rossen, J. Wesseling, M. C. Horzinek, P. J. M. Rottier
      Pages 11-16
    4. A. Paul Reed, Sharon Klepfer, Timothy Miller, Elaine Jones
      Pages 17-21
    5. P. Britton, S. Kottier, C.-M. Chen, D. H. Pocock, H. Salmon, J. M. Aynaud
      Pages 29-34
    6. Luis Enjuanes, Carlos Sánchez, Fátima Gebauer, Ana Méndez, Joaquín Dopazo, María L. Ballesteros
      Pages 35-42
    7. Kurt Tobler, Anne Bridgen, Mathias Ackermann
      Pages 49-54
    8. M. Duarte, J. Gelfi, P. Lambert, D. Rasschaert, H. Laude
      Pages 55-60
    9. Jens Herold, Thomas Raabe, Stuart G. Siddell
      Pages 75-79
  3. Transcription, Replication and Genome Engineering

    1. Front Matter
      Pages 83-83
    2. Mary C. Schaad, Wan Chen, Sheila A. Peel, Ralph S. Baric
      Pages 85-90
    3. Julian Hiscox, David H. Pocock, Paul Britton
      Pages 99-104
    4. Stanley Tahara, Cornelia Bergmann, Gary Nelson, Richard Anthony, Therese Dietlin, Shigeru Kyuwa et al.
      Pages 111-116
    5. Julian L. Leibowitz, S. Jeffrey Reneker
      Pages 117-122
    6. Dave Cavanagh, Kathy Shaw, Zhao Xiaoyan
      Pages 123-128
    7. Tetsuya Mizutani, Masanobu Hayashi, Akihiko Maeda, Nobuya Sasaki, Tadashi Yamashita, Noriyuki Kasai et al.
      Pages 129-135
    8. Paul S. Masters, Cheri A. Koetzner, Ding Peng, Monica M. Parker, Cynthia S. Ricard, Lawrence S. Sturman
      Pages 143-148
  4. Characterization and Functions of Viral Proteins

    1. Front Matter
      Pages 155-155
    2. James L. Gombold, Susan T. Hingley, Susan R. Weiss
      Pages 157-163
    3. Fumihiro Taguchi, Toshio Ikeda, Keiichi Saeki, Hideyuki Kubo, Tateki Kikuchi
      Pages 171-175
    4. Bettina Grosse, Stuart G. Siddell
      Pages 177-182
    5. Emilia L. Oleszak, Stanley Perlman, Rebecca Parr, Ellen W. Collisson, Julian L. Leibowitz
      Pages 183-188
    6. Dirk Jan E. Opstelten, Marian C. Horzinek, Peter J. M. Rottier
      Pages 189-195
    7. H. Vennema, L. Heijnen, P. J. M. Rottier, M. C. Horzinek, W. J. M. Spaan
      Pages 209-214
    8. Scott A. Hughes, Mark R. Denison, Pedro Bonilla, Julian L. Leibowitz, Ralph S. Baric, Susan R. Weiss
      Pages 221-226
    9. Eric J. Snijder, Alfred L. M. Wassenaar, Willy J. M. Spaan
      Pages 227-232
  5. Coronaviruses, Toroviruses and Arteriviruses: Common and Distinctive Features

    1. Front Matter
      Pages 233-233
    2. Eric J. Snijder, Marian C. Horzinek, Willy J. M. Spaan
      Pages 235-244
    3. Antoine A. F. de Vries, Ewan D. Chirnside, Marian C. Horzinek, Peter J. M. Rottier
      Pages 245-253
    4. D. Cavanagh, D. A. Brian, M. A. Brinton, L. Enjuanes, K. V. Holmes, M. C. Horzinek et al.
      Pages 255-257
  6. Cellular Receptors for Coronaviruses

    1. Front Matter
      Pages 259-259
    2. Kathryn V. Holmes, Gabriela Dveksler, Sara Gagneten, Curtis Yeager, Sue-Hwa Lin, Nicole Beauchemin et al.
      Pages 261-266
    3. G. S. Dveksler, A. A. Basile, C. B. Cardellichio, N. Beauchemin, C. W. Dieffenbach, K. V. Holmes
      Pages 267-272

About this book


Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.


Polypeptide gene expression genetic engineering molecular biology polymer protein virus

Editors and affiliations

  • Hubert Laude
    • 1
  • Jean-François Vautherot
    • 1
  1. 1.Institut National de la Recherche Agronomique (INRA)Jouy-en-JosasFrance

Bibliographic information

  • DOI
  • Copyright Information Plenum Press, New York 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6305-7
  • Online ISBN 978-1-4615-2996-5
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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