Quantitative Assessment in Epilepsy Care

  • Harry Meinardi
  • Joyce A. Cramer
  • Gus A. Baker
  • Antonio Martins da Silva

Part of the NATO ASI Series book series (NSSA, volume 255)

Table of contents

  1. Front Matter
    Pages i-viii
  2. A. Martins da Silva, E. Lourenço, J. M. Nunes, D. Mendonça
    Pages 35-42
  3. César Viteri, José Manuel Martínez-Lage
    Pages 49-54
  4. Joyce A. Cramer, Richard H. Mattson
    Pages 55-71
  5. Harry Meinardi, Joyce A. Cramer, Gus A. Baker, Antonio Martins da Silva
    Pages 73-81
  6. Aristides Kazis, Sevasti Bostantjopoulou
    Pages 83-93
  7. D. G. A. Kasteleijn-Nolst Trenité
    Pages 103-107
  8. Y. A. Hekster, D. J. P. Wijsman, E. W. Wuis, T. B. Vree, H. Meinardi
    Pages 109-116
  9. M. W. Lammers, H. Meinardi
    Pages 117-122
  10. Richard H. Mattson, Joyce A. Cramer
    Pages 123-135
  11. Jan Vermeulen, Raphael Canger
    Pages 145-153
  12. Albert P. Aldenkamp
    Pages 155-161
  13. David Chadwick, Ann Jacoby
    Pages 171-176
  14. Bert Spilker
    Pages 177-184
  15. Dave Smith, Gus Baker, M. Clin
    Pages 185-199
  16. Back Matter
    Pages 201-214

About this book


Advances in epilepsy in recent decades have allowed for improved algorithms for diagnosis and a common understanding of terminology with the development of the International Classifications of Seizures and the Epilepsies. Nevertheless, no common system exists for the estimation of epilepsy severity or its impact on quality of life. Therefore, epileptologists lack the ability to make quantitative assessments of individual patients for comparison of care or for meta-analyses in clinical trials. This book on the Quantitative Assessment of Epilepsy Care approaches this omission by addressing the potential application of clinimetrics within the framework of epilepsy treatment. Clinimetrics is a fast growing discipline concerned with the quantification of clinical symptoms with respect to decision making relating to diagnosis, treatment, and prognosis. These methods allow for the development and validation of clinical scoring systems. For example, the Glasgow Coma Scale is widely used. As a chronic disorder, epilepsy would benefit from clinimetric methodology to create uniformity and to allow for comparisons among evaluations. In addition, epileptologists have not yet developed assessments of health related quality of life to define the overall condition of the chronic epilepsy patient and various therapeutic endpoints. While clini­ metric tools are essential for research, they will also be useful in clinical practice for the care of individual patients by documenting status and changes over time. This treatise will provide critical analyses of whether existing rating scales and techniques are valid to use, and which types of scales and techniques require further development.


assessment care classification clinical trial development diagnosis drug epilepsy methodology patients quality quality of life research therapy treatment

Editors and affiliations

  • Harry Meinardi
    • 1
  • Joyce A. Cramer
    • 2
    • 3
  • Gus A. Baker
    • 4
  • Antonio Martins da Silva
    • 5
  1. 1.Instituut voor EpilepsiebestrijdingHeemstedeThe Netherlands
  2. 2.Department of Veterans Affairs Medical CenterWest HavenUSA
  3. 3.Yale UniversityNew HavenUSA
  4. 4.The Walton CentreLiverpoolUK
  5. 5.Hospital Geral de Santo António and Institute of Biomedical SciencesUniversity of PortoPortoPortugal

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6302-6
  • Online ISBN 978-1-4615-2990-3
  • Buy this book on publisher's site
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