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Retinal Degeneration

Clinical and Laboratory Applications

  • Joe G. Hollyfield
  • Robert E. Anderson
  • Matthew M. LaVail

Table of contents

  1. Front Matter
    Pages i-xiv
  2. The Macula, Aging and Macular Degeneration

    1. Front Matter
      Pages 1-1
    2. C. Kathleen Dorey, Giovanni Staurenghi, Francois C. Delori
      Pages 3-14
    3. Michael B. Gorin, Carmella Sarneso, T. Otis Paul, Julielani Ngo, Daniel E. Weeks
      Pages 35-47
    4. Manfred Stuhrmann, Astrid Spangenberg, Albert Schinzel, Jörg Schmidtke
      Pages 49-52
    5. John Wells, John Wroblewski, Jeffrey Keen, Christopher Inglehearn, Christopher Jubb, Anja Eckstein et al.
      Pages 53-59
  3. Retinitis Pigmentosa and Allied Retinal Degenerations: Molecular, Cellular and Clinical Studies

    1. Front Matter
      Pages 61-61
    2. G. Jane Farrar, Siobhán A. Jordan, Rajendra Kumar-Singh, Chris F. Inglehearn, Andreas Gal, Cheryl Greggory et al.
      Pages 63-77
    3. Maurizio Fossarello, Antonina Serra, David Mansfield, Alan Wright, Jorgos Loudianos, Mario Pirastu et al.
      Pages 79-90
    4. Giuseppe Del Porto, Enzo M. Vingolo, Dezsö David, Katharina Steindl, Heike Wedemann, Renato Forte et al.
      Pages 91-101
    5. Birgit Lorenz, Christine Hörmann, Monika Horn, Thomas Berninger, Monika Döring, Andreas Gal
      Pages 103-114
    6. Eckart Apfelstedt-Sylla, Susanna Bunge, Dezsö David, Klaus Rüther, Andreas Gal, Eberhart Zrenner
      Pages 115-125
    7. Radha Ayyagari, Richard J. H. Smith, Elizabeth C. Lee, William J. Kimberling, Marcelle Jay, Alan Bird et al.
      Pages 127-133
    8. Thomas Meitinger, Alfons Meindl, Wolfgang Berger, Hans-Hilger Ropers
      Pages 135-142
    9. Hélène Dollfus, Jean-Michal Rozet, Oliver Delrieu, Alain Vignal, Imhad Ghazi, Jean-Louis Dufier et al.
      Pages 143-152
    10. Anne-Françoise Roux, Johanna Rommens, Maria A. Musarella
      Pages 153-160
    11. Stephen P. Daiger
      Pages 161-170
  4. Studies of Retinal Degeneration Using Transgenic Mice and Other Animal Models

    1. Front Matter
      Pages 199-199
    2. Muna I. Naash, Muayyad R. Al-Ubaidi, Joe G. Hollyfield, Wolfgang Baehr
      Pages 201-210
    3. Janis Lem, John G. Flannery, Debora B. Farber, Meredithe L. Applebury, Carol Raport, James B. Hurley et al.
      Pages 231-242
    4. Muayyad R. Al-Ubaidi, Joe G. Hollyfield, Ramon L. Font, Wolfgang Baehr
      Pages 243-250
    5. Richard L. Hurwitz, Steven J. Pittler, Michael L. Suber, Ning Qin, Rehwa H. Lee, Cheryl M. Craft et al.
      Pages 251-258
    6. Nicolas G. Bazan, Elena B. Rodriguez de Turco, William C. Gordon, Virginia C. Strand, Rex E. Martin
      Pages 259-271
    7. John R. Heckenlively, Bo Chang, Chen Peng, Norman L. Hawes, Thomas H. Roderick
      Pages 273-280
    8. P. Watson, A. Wrigstad, R. C. Riis, K. Narfstrom, P. G. C. Bedford, S. E. G. Nilsson
      Pages 281-290
  5. Agents Which Cause or Prevent Retinal Degeneration

    1. Front Matter
      Pages 291-291
    2. Matthew M. LaVail, Kazuhiko Unoki, Douglas Yasumura, Michael T. Matthes, Roy H. Steinberg
      Pages 293-298
    3. Martin F Humphrey, Yi Chu, Carol Parker, Ian J Constable
      Pages 299-308
    4. Michael Tytell, Keiko Yamaguchi, Katsuhiro Yamaguchi
      Pages 309-320
    5. Jun Fu, Tim T. Lam, Nancy J. Mangini, Mark O. M. Tso
      Pages 321-333
    6. Ann H. Milam, Kenneth R. Alexander, Samuel G. Jacobson, John C. Saari, Wojciech P. Lubinski, Lynn G. Feun et al.
      Pages 335-342
    7. Nicola Orzalesi, Luca Migliavacca, Stefano Miglior
      Pages 343-353
  6. Back Matter
    Pages 361-365

About this book

Introduction

During the last few years, an explosion of infonnation has come from human genetics and molecular and cell biological studies as to the genetic basis for a number of fonns of inherited retinal degenerations. These disorders have plagued mankind for millennia because they take from otherwise healthy individuals the precious gift of sight. The fundamental advances in recent years have identified a number of genes involved in the groups of diseases which hopefully will lead to discoveries that may, in the not too distant future, allow the prevention and possible cure of some of these blinding eye disorders. To foster a forum for discussions of studies on degenerative retinal disorders, we convened a symposium on retinal degenerations in 1984, at the VIth International Congress of Eye Research Meeting, held in Alicante, Spain. Because of the success of this meeting and the subsequent publication, we have since organized a series of biennial satellite meetings on retinal degenerations for the ISER congresses held in Nagoya, Japan (1986), San Francisco (1988) and Helsinki (1990). Each of these satellite symposium on retinal degenerations was accompanied by a published proceedings volume. This volume is the fifth in this series and contains the proceedings of the Sardinia Symposium on Retinal Degeneration held September 15-20, 1992, as a satellite meeting of the 10th International Congress of Eye Research.

Keywords

aging eye genes genetics growth macular degeneration metabolism mutation retina

Editors and affiliations

  • Joe G. Hollyfield
    • 1
  • Robert E. Anderson
    • 1
  • Matthew M. LaVail
    • 2
  1. 1.Cullen Eye InstituteBaylor College of MedicineHoustonUSA
  2. 2.Beckman Vision CenterUniversity of California, San FranciscoSan FranciscoUSA

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