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Translational Regulation of Gene Expression 2

  • Joseph Ilan
Book

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. G. Wesley Hatfield
    Pages 1-22
  3. Claude Portier, Marianne Grunberg-Manago
    Pages 23-47
  4. Knud H. Nierhaus, Francisco Triana
    Pages 49-68
  5. Alan G. Hinnebusch, Ronald C. Wek, Thomas E. Dever, A. Mark Cigan, Lan Feng, Thomas F. Donahue
    Pages 87-115
  6. Fred Sherman, Richard P. Moerschell, Susumu Tsunasawa, Rolf Sternglanz, Mark E. Dumont
    Pages 117-141
  7. Robert M. Frederickson, Nahum Sonenberg
    Pages 143-162
  8. Rostom Bablanian
    Pages 187-202
  9. Bayar Thimmapaya, Ghanashyam D. Ghadge, Prithi Rajan, Sathyamangalam Swaminathan
    Pages 203-225
  10. Robert J. Schneider, Yan Zhang
    Pages 227-250
  11. G. C. Candelas, G. Arroyo, C. Carrasco, E. Carrasquillo, A. Plazaola, M. Irizarry
    Pages 251-264
  12. Steven Sczekan, Dong-Hee Lee, Dieter Techel, Maria Mittag, J. Woodland Hastings
    Pages 265-277
  13. Susan Lindquist
    Pages 279-320
  14. William E. Walden
    Pages 321-334
  15. Roger L. Kaspar, David R. Morris, Michael W. White
    Pages 335-348
  16. Jane-Jane Chen
    Pages 349-372
  17. Gisela Kramer, Wieslaw Kudlicki, Boyd Hardesty
    Pages 373-390
  18. William C. Merrick, Donald D. Anthony
    Pages 391-403
  19. Naba K. Gupta, Bansidhar Datta, Manas K. Ray, Ananda L. Roy
    Pages 405-431
  20. Alexey G. Ryazanov, Alexander S. Spirin
    Pages 433-455
  21. Katherine T. Schmeidler-Sapiro, Joseph Ilan
    Pages 457-484
  22. Back Matter
    Pages 485-493

About this book

Introduction

This book, which results from the dramatic increase in interest in the control mechanism employed in gene expression and the importance of the regulated proteins, presents new information not covered in Translational Regulation of Gene Expression, which was published in 1987. It is not a revision of the earlier book but, rather, an extension of that volume witl, special emphasis on mecha­ nIsm. As the reader will discover, there is enormous diversity in the systems employing genes for translational regulation in order to regulate the appearance of the final product-the protein. Thus, we find that important proteins such as protooncogenes, growth factors, stress proteins, cytokines, lymphokines, iron­ storage and iron-uptake proteins, and a panorama of prokaryotic proteins, as well as eukaryotic viral proteins, are translationally regulated. Since for some gene products the degree of control is greater by a few orders of magnitude than their transcription, we can state that for these genes, at least, the expression is translationall y controlled. Translational regulation of gene expression in eukaryotes has emerged in the last few years as a major research field. The present book describes mechanisms of translational regulation in bacteria, yeast, and eukaryotic viruses, as well as in eukaryotic genes. In this book we try to provide in-depth coverage by including important examples from each group rather than systematically including all additional systems not described in the previous volume.

Keywords

Elongation Translation gene expression genes genetics ribosomal proteins saccharomyces cerevisiae

Editors and affiliations

  • Joseph Ilan
    • 1
  1. 1.Institute of PathologyCase Western Reserve University School of MedicineClevelandUSA

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