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Mechanism of Myofilament Sliding in Muscle Contraction

  • Haruo Sugi
  • Gerald H. Pollack
Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 332)

Table of contents

  1. Kinetic Properties of Actin-Myosin Sliding in Muscle Studied by Flash Photolysis of Caged Substances and Temperature Jump

  2. Kinetic Properties of Actin-Myosin Sliding Studied with Demembranated Systems

    1. Front Matter
      Pages 527-527
    2. Shin’ichi Ishiwata, Takashi Anazawa, Takashi Fujita, Norio Fukuda, Hideharu Shimizu, Kenji Yasuda
      Pages 545-556
    3. R. T. Tregear, E. Townes, J. Gabriel, C. Ellington
      Pages 557-565
    4. Masataka Kawai, Yan Zhao, Herbert R. Halvorson
      Pages 567-580
    5. William F. Harrington, Trudy Karr, William B. Busa
      Pages 603-613
    6. T. Kobayashi, K. Noguchi, T. Gross, H. Sugi
      Pages 615-621
  3. Kinetic Properties of Actin-Myosin Sliding with Intact Muscle Fibers

    1. Front Matter
      Pages 623-623
    2. P. W. Brandt, F. Colomo, C. Poggesi, C. Tesi
      Pages 627-637
    3. Yasutake Saeki, Satoshi Kurihara, Kenichi Hongo, Etsuko Tanaka
      Pages 639-648
    4. Henk EDJ ter Keurs, Pieter P. de Tombe
      Pages 649-665
    5. Gerald H. Pollack, Arie Horowitz, Manfred Wussling, Károly Trombitás
      Pages 679-690
    6. Gabriella Piazzesi, Marco Linari, Vincenzo Lombardi
      Pages 691-701
    7. M. A. Bagni, G. Cecchi, F. Colomo, P. Garzella
      Pages 703-714
  4. Kinetic Properties of Actin-Myosin Sliding Studied by Energetics Experiments

    1. Front Matter
      Pages 725-725
    2. Nancy A. Curtin, Roger C. Woledge
      Pages 729-734
    3. Roger C. Woledge, Nancy A. Curtin
      Pages 735-747
    4. Martin J. Kushmerick, Timothy S. Moerlandt, Robert W. Wiseman
      Pages 749-761
  5. Back Matter
    Pages 785-866

About this book

Introduction

This volume presents the entire proceedings of the symposium organized by one of us (H. S. ) on November 11 to 15, 1991 at Hakone, Japan, under the title of "Mechanism of Myofllament Sliding in Muscle Contraction. " Among various kinds of energy transduction mechanisms in biological systems, the mechanism of muscle contraction has been studied most intensively and extensively over many years. Since the monumental discovery by the two Huxleys and coworkers that muscle contraction results from relative sliding between the thick and thin myofilaments, attention of muscle investigators has been focused on the question, what makes the fllaments slide past one another. In response to the above question, A. F. Huxley and Simmons put forward a contraction model in 1971, in which globular heads of myosin (cross-bridges) extending from the thick fllament first attach to actin on the thin fllament, and then change their angle of attachment to actin (power stroke) leading to force generation or myofilament sliding until they detach from the thin fllament. The rocking cross-bridge contraction model seemed to be entirely consistent with the kinetic scheme of actomyosin ATPase published by Lymn and Taylor at the same time, thus giving a strong impression to the people concerned that the muscle contraction mechanism would soon be sorted out. In his review lecture in 1974, however, A. F.

Keywords

ATP ATPase X-ray smooth muscle temperature

Editors and affiliations

  • Haruo Sugi
    • 1
  • Gerald H. Pollack
    • 2
  1. 1.Teikyo UniversityTokyoJapan
  2. 2.University of WashingtonSeattleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-2872-2
  • Copyright Information Plenum Press, New York 1993
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6245-6
  • Online ISBN 978-1-4615-2872-2
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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