Mammary Tumorigenesis and Malignant Progression

Advances in Cellular and Molecular Biology of Breast Cancer

  • Robert B. Dickson
  • Marc E. Lippman

Part of the Cancer Treatment and Research book series (CTAR, volume 71)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Proliferation, Differentiation, and Malignant Progression

  3. Genetic Basis for Cancer Onset and Progression

    1. Front Matter
      Pages 49-49
    2. Mary-Claire King, Sarah Rowell
      Pages 51-62
    3. D. Craig Allred, Richard Elledge, Gary M. Clark, Suzanne A. W. Fuqua
      Pages 63-77
    4. Carlos A. Encarnacion, Suzanne A. W. Fuqua
      Pages 97-109
  4. Growth Factors, Receptors, and Polyamines

  5. Cancer Cell Adhesion, Migration, and Proteolysis

    1. Front Matter
      Pages 227-227
    2. Pierre Savagner, Brigitte Boyer, Ana Maria Valles, Jacqueline Jouanneau, Jean Paul Thiery
      Pages 229-249
    3. Jürgen Behrens, Walter Birchmeier
      Pages 251-266
    4. Maura C. Kibbey, Keizo Yamamura, Soo Han Jun, Derrick S. Grant, Hynda K. Kleinman
      Pages 267-275
    5. Seth L. Schor, Anne Marie Grey, Ian Ellis, Ana M. Schor, Anthony Howell, Philip Sloan et al.
      Pages 277-298
    6. Nils Brünner, Charles Pyke, Claus Holst Hansen, John Rømer, Jan Grøndahl-Hansen, Keld Danø
      Pages 299-309
  6. Rodent Model Systems of Breast Cancer

    1. Front Matter
      Pages 311-311
    2. Katherine McKenzie, Saraswati Sukumar
      Pages 313-329
    3. Clive Dickson, Vera Fantl
      Pages 331-343
  7. Back Matter
    Pages 345-361

About this book


The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth factors, hormones, tumor-host interactions, and determinants of metastases. Since our last volume, research in breast cancer has continued to proceed at an explosive rate. We hope the current volume will provide the reader with some of the excitement felt by the editors and authors as we begin to understand this all-too-common disease. The first section of this book is devoted to the basic processes of proli­ feration, differentiation, and malignant progression of breast cancer. T.l. Anderson and W.R. Miller lead off with a detailed description of controls on proliferation in the normal human breast and in breast cancer. This chapter strongly emphasizes pathological aspects. The second chapter, by M.R. Stampfer and P. Yaswen, presents a corresponding viewpoint through a presentation of experiments with human mammary epithelial cells in culture. The second section of the book emphasizes the genetic basis for breast cancer onset and malignant progression. Chapter 3, by M.-C. King and S.


angiogenesis biology carcinogenesis carcinoma genes hormones metastasis molecular biology oncogene ovarian cancer proliferation steroids tumor tumor growth tumorigenesis

Editors and affiliations

  • Robert B. Dickson
    • 1
  • Marc E. Lippman
    • 1
  1. 1.Lombardi Cancer Research CenterGeorgetown University School of MedicineUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6109-1
  • Online ISBN 978-1-4615-2592-9
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site
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