© 1994

Purine and Pyrimidine Metabolism in Man VIII

  • Amrik Sahota
  • Milton W. Taylor

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 370)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Review

  3. Regulation of Purine and Pyrimidine Metabolism

    1. Clinical

      1. Makoto Usami, Koji Furuchi, Hiroshi Kasahara, Seiji Haji, George Kotani, Atsunori Iso et al.
        Pages 11-14
      2. Claude Bory, Christiane Chantin, Roselyne Boulieu
        Pages 15-18
      3. Maciej Marlewski, Ryszard T. Smolenski, Julian Swierczynski, Boleslaw Rutkowski, John A. Duley, H. Anne Simmonds et al.
        Pages 19-22
      4. Tina Kristensen, Helle Kock Jensen, Birgitte Munch-Petersen
        Pages 23-26
    2. Gout

      1. Kiyoko Kaneko, Shin Fujimori, Hisashi Yamanaka, Ieo Akaoka
        Pages 27-30
      2. Yuji Moriwaki, Tetsuya Yamamoto, Sumio Takahashi, Yumiko Nasako, Toshikazu Hada, Kazuya Higashino
        Pages 39-42
      3. Yumiko Nasako, Tetsuya Yamamoto, Yuji Moriwaki, Sumio Takahashi, Zenta Tsutsumi, Toshikazu Hada et al.
        Pages 43-46
      4. B. Porcelli, D. Vannoni, R. Leoncini, M. Pizzichini, R. Pagani, E. Marinello
        Pages 47-52
      5. Hisashi Yamanaka, Naoyuki Kamatani, Masayuki Hakoda, Chihiro Terai, Ryuji Kawaguchi, Sadao Kashiwazaki
        Pages 53-56
      6. A. Pelatti, C. P. Quaratino, C. D’ Amario, R. Tentarelli, G. Riario Sforza, A. Giacomello
        Pages 57-60
      7. Juan G. Puig, Felícitas A. Mateos, Ma. E. Miranda, Rosa J. Torres, Eugenio de Miguel, Carlos Pérez de Ayala et al.
        Pages 69-72
      8. I. Sebesta, J. Krijt, K. Pavelka, J. Maly, H. A. Simmonds, M. B. McBride
        Pages 73-76
      9. N. Di Sciascio, C. P. Quaratino, C. Rucci, P. Ciaglia, M. N. Mariani, A. Giacomello
        Pages 77-78

About this book


These volumes record the presentations made at the VIII International Symposium on Purine and Pyrimidine Metabolism in Manheld at Indiana University, Bloomington, USA from May 22- May 27, 1994. This was a continuation of meetings held every three years with the idea of bringing clinicians and basic scientists together, which we hope results in cross-fertilization of ideas. Some of the papers presented in this volume represent oral contributions and others are from posters, but we emphasize that both are considered of equal merit. As is obvious from a perusal of the titles of the papers there has been a shift in the focus of this meeting, which reflects a general shift in the area of purine and pyrimidine metabolism. The emphasis has definitely shifted to gene structure and molecular genetics, with the beginnings we hope of gene therapy as an important branch of this area of science. Although many of the inherited diseases discussed in this text can be treated with drugs, the major thrust in the futurewill be in gene therapy, where the gene (or cDNA) will be used to treat the patient with enzyme deficiency, particularly if the patient is young. As can be seen from the Iist of authors there is a remarkable degree of international cooperation in this area across countries and continents. We thank the many participants who have attended these symposia many times, and we welcome the large group of scientists from Eastern Europe who are attending this meeting for the first time.


Purine Pyrimidine enzymes gene therapy metabolism

Editors and affiliations

  • Amrik Sahota
    • 1
  • Milton W. Taylor
    • 2
  1. 1.Indiana University School of MedicineIndianapolisUSA
  2. 2.Indiana UniversityBloomingtonUSA

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