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Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment

  • Roberto L. Ceriani

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 353)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Jerry A. Peterson, Roberto L. Ceriani
    Pages 1-8
  3. Pei-Xiang Xing, Vasso Apostolopoulos, Joe Trapani, Julie Prenzoska, Ian F. C. McKenzie
    Pages 9-16
  4. Daniel H. Wreschner, Sheila Zrihan-Licht, Amos Baruch, Dalit Sagiv, Mor-li Hartman, Nechama Smorodinsky et al.
    Pages 17-26
  5. Luciano Ozzello, Carolyn M. De Rosa, David V. Habif Sr., Edward W. Blank, Roberto L. Ceriani, Kari Cantell
    Pages 35-46
  6. Joseph R. Couto, Edward W. Blank, Jerry A. Peterson, Radwan Kiwan, Roberto L. Ceriani, Eduardo A. Padlan
    Pages 55-59
  7. T. S. Baker, H. M. Caskey-Finney, D. J. King, A. D. G. Lawson, A. Lyons, A. Mountain et al.
    Pages 61-82
  8. Paul Carter, Maria L. Rodrigues, Gail D. Lewis, Irene Figari, M. Refaat Shalaby
    Pages 83-94
  9. James W. Dennis, Bernard Fernandez, Bozena Korczak, Paul Goss, Michael Baker
    Pages 95-104
  10. Nechama I. Smorodinsky, Ronit Yarden, Lior Carmon, Daniel H. Wreschner, Iafa Keydar, Mara Hareuveni
    Pages 125-137
  11. Malaya Bhattacharya-Chatterjee, Ewe Mrozek, Sonjoy Mukerjee, Roberto L. Ceriani, Heinz Kohler, Kenneth A. Foon
    Pages 139-148
  12. Roberto L. Ceriani, Frank Baratta, Ramon J. Gaslonde, Carolyn M. De Rosa, Luciano Ozzello
    Pages 155-167
  13. Geoffrey A. Pietersz, Kenia Krauer, Ian F. C. McKenzie
    Pages 169-179
  14. Elissa L. Kramer, Sally J. DeNardo, Leonard Liebes, Marilyn E. Noz, Linda Kroger, Stephan D. Glenn et al.
    Pages 181-192
  15. Kapil Dhingra, Daniel Booser, Aman Buzdar, Martin Raber, Lia Gutierrez, Gabriel Hortobagyi et al.
    Pages 193-202
  16. S J. DeNardo, L. F. O’Grady, C. M. Richman, G. L. DeNardo
    Pages 203-211
  17. Back Matter
    Pages 213-222

About this book

Introduction

Today, advances in the area of immunology and breast cancer are made at an increasing rate, yielding an amount of information that can become unwieldy. The opportunity for scientists in this area of research to gather together to exchange results and working hypotheses represents, in my belief, a very attractive proposition. With this in mind, these workshops have been convened with two year intervals for the last ten years. In each of them, selected topics have been highlighted. The present workshop underscores the large advancements made in the molecular biology of both breast cancer associated antigens and their corresponding antibodies. Understanding the genetic information for the expression of these antigens has been recently advanced leading to preparation of molecularly engineered reagents for use in vaccination, serum assays, and immunizations for novel antibody production. In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing. Clinical studies using anti-breast murine antibody continue to be carried out and are presented at this meeting establishing a base line for safety and efficaciousness in imaging and immunotherapy that it is hoped will be superseded by the humanized forms. Basic immunology and immunochemistry studies in breast cancer are also included in this workshop that demonstrate the fast pace at which this research is advancing in many laboratories worldwide.

Keywords

Antigen Expression base chemistry imaging preparation

Editors and affiliations

  • Roberto L. Ceriani
    • 1
  1. 1.Cancer Research Fund of Contra CostaWalnut CreekUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-2443-4
  • Copyright Information Plenum Press, New York 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6038-4
  • Online ISBN 978-1-4615-2443-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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