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  • © 1994

The Cell Cycle

Regulators, Targets, and Clinical Applications

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Table of contents (48 chapters)

  1. Cell Cycle Control of Gene Expression and Repair

    1. Activation of the Heat Shock Transcription Factor During G1

      • Jacqueline L. Bruce, Brendan D. Price, Stuart K. Calderwood
      Pages 155-161
    2. DNA Damage and Cell Cycle Regulation in S. Cerevisiae

      • Stephen J. Elledge, Zheng Zhou, James B. Allen, Tony A. Navas, William J. Jones
      Pages 163-166
  2. Mitosis: Induction and Mechanics

    1. Front Matter

      Pages 173-173
    2. Direct Inhibition of p107WEE1 by the Nim 1/CDR 1 Kinase

      • Laura L. Parker, Sarah A. Walter, Helen Piwnica-Worms
      Pages 175-184
    3. Regulation of Nuclear Envelope Assembly and Disassembly by ARF and other GTP-Binding Proteins

      • Annette L. Boman, Kathleen M. C. Sullivan, Katherine L. Wilson
      Pages 197-202
    4. Possible Role of the Multi Catalytic Proteinase (Proteasome) in Regulating of the Cell Cycle

      • A. Amsterdam, F. Pitzer, U. Santarius, A. Dantes, W. Baumeister
      Pages 203-209
    5. Analysis of Centrosome Replication Events in Mammalian Cells

      • Ron Balczon, Liming Bao, Warren E. Zimmer, Kevin Brown, Raymond P. Zinkowski, B. R. Brinkley
      Pages 229-235
  3. Cell Cycle Regulation in Development

    1. Front Matter

      Pages 245-245
    2. Mos Proto-Oncogene and Cell Cycle Regulation

      • George F. Vande Woude, Taesaeng Choi, Renping Zhou, Monica Murakami, Wayne Matten, Kenji Fukasawa
      Pages 247-249
    3. Altered Regulation of Cell Cycle Genes and Proteins in Senescent Human Diploid Fibroblasts

      • Gretchen H. Stein, Linda F. Drullinger, Emma Lees, Steven I. Reed, Vjekoslav Dulić
      Pages 251-262
    4. Cell Proliferation as a Biomarker of Age and Development

      • M. H. Lu, S. F. Ali, D. S. He, A. Turturro, R. W. Hart
      Pages 263-269
    5. Heat Shock Genes and Cell Cycle Regulation During Early Mammalian Development

      • David Walsh, Li Zhe, Frank Zeng, Wu Yan, Karen Li
      Pages 271-281
    6. Expression of G1 Cyclins During Early Development of Zebrafish Embryos

      • Anat Yarden, Zvi Kam, Benjamin Geiger
      Pages 283-289
    7. Apoptosis: Definition, Roles and Regulation

      • L. E. Gerschenson, R. J. Rotello, R. Lieberman, C.-I. Sze
      Pages 291-299

About this book

Interest in the cell cycle has grown explosively in recent years as a result of the identification of key cell cycle regulators and their substrates. Aside from enhancing our understanding of normal cellular growth controls, this new knowledge has also becn valuable in elucidating mechanisms of growth deregulation which occur in diseased states, such as cancer and, in some instances, viral or parasitic infections. The Thirteenth Washington International Spring Symposium was organized with the intention of bringing together scientists working on different aspects of the cell cycle. Scientific topics presented ranged from molecular regulators and effectors to mitosis­ specific changes in cell architecture to the role of the cell cycle in development and disease. The goal of this gathering was to help formulate a more comprehensive and integrated picture of events driving and being driven by the cell cycle, as well as to evaluate the possibilities for clinical application of this knowledge. This symposium, held in Washington, D.C. from May 10-14, 1993, was attended by more than 400 scientists from 20 countries, including many of the scientific leaders in this field. This volume contains most of the papers presented at the seven plenary sessions in addition to selected contributions from a total of nine special oral and poster sessions.

Editors and Affiliations

  • The George Washington University Medical Center, USA

    Valerie W. Hu

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access