Lacrimal Gland, Tear Film, and Dry Eye Syndromes

Basic Science and Clinical Relevance

  • David A. Sullivan

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 350)

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Keynote Address

    1. Darlene A. Dartt
      Pages 1-9
  3. Lacrimal Gland: Anatomy and Innervation

    1. Benjamin Walcott, Roger H. Cameron, Peter R. Brink
      Pages 11-18
    2. Peter Seifert, Manfred Spitznas, Frank Koch, Andrea Cusumano
      Pages 19-23
    3. Jaipaul Singh, Ernest Adeghate, Shuna Burrows, Frank C. Howarth, Ruth M. Williams
      Pages 25-30
    4. B. Britt Bromberg, Cynthia W. Hanemann, Mary H. Welch, Roger W. Beuerman, Sherwood Githens
      Pages 31-36
    5. Gordon W. Laurie, J. Douglas Glass, Rebecca A. Ogle
      Pages 37-44
    6. Winrich Breipohl, Manfred Spitznas, Fred Sinowatz, Oliver Leip, Wallid Naib-Majani, Andrea Cusumano
      Pages 45-48
    7. Orkan George Stasior, Janet L. Roen
      Pages 49-52
    8. Jaipaul Singh, Ernest Adeghate, Shuna Burrows, Frank C. Howarth, Tibor Donath
      Pages 57-60
    9. Benjamin Walcott, Roger Cameron, Elizabeth Grine, Elizabeth Roemer, Monica Pastor, Peter R. Brink
      Pages 61-65
    10. Ruth M. Williams, Jaipaul Singh, Keith A. Sharkey
      Pages 67-74
    11. Richard L. Wood, Kyung-Ho Park, J. Peter Gierow, Austin K. Mircheff
      Pages 75-77
  4. Lacrimal Gland: Electrophysiology, Water and Ion Transport

    1. Austin K. Mircheff, Ross W. Lambert, Robert W. Lambert, Carol A. Maves, J. Peter Gierow, Richard L. Wood
      Pages 79-86
    2. Dwight W. Warren, Ana Maria Azzarolo, Laren Becker, Kirsten Bjerrum, Renee L. Kaswan, Austin K. Mircheff
      Pages 99-104
    3. Peter Reinach, Vadivel Ganapathy, Viviana Torres-Zamorano
      Pages 105-110
    4. J. Peter Gierow, Richard L. Wood, Austin K. Mircheff
      Pages 111-114
  5. Lacrimal Gland: Signal Transduction and Protein Secretion

    1. James W. Putney Jr., Gary St. J. Bird
      Pages 115-119
    2. Michele M. Cripps, D. Jean Bennett
      Pages 127-132
    3. Roger H. Cameron, Benjamin Walcott, S. F. Fan, Monica Pastor, Elizabeth Roemer, Elizabeth Grine et al.
      Pages 133-139
    4. Ronald D. Schoenwald, Charles F. Barfknecht, Satish Shirolkar, Erning Xia, Christopher C. Ignace
      Pages 141-146
    5. Robin R. Hodges, Deanna M. Dicker, Darlene A. Dartt
      Pages 147-150
    6. Peter R. Brink, Benjamin Walcott, Elizabeth Roemer, Roger Cameron, Monica Pastor
      Pages 151-156
    7. Flavio Jaime Rocha, Robin S. Kelleher, Joan A. Edwards, Janethe D. O. Pena, Masafumi Ono, David A. Sullivan
      Pages 157-160
  6. Lacrimal Gland: Immunology

    1. P. C. Montgomery, N. L. O’Sullivan, L. B. Martin, C. A. Skandera, J. V. Peppard, A. G. Pockley
      Pages 161-168
    2. Ross W. Lambert, Robin S. Kelleher, L. Alexandra Wickham, Jianping Gao, David A. Sullivan
      Pages 175-180
    3. Nancy L. O’Sullivan, Rajiv Raja, Paul C. Montgomery
      Pages 181-184
    4. Masafumi Ono, Kenichi Yoshino, Kazuo Tsubota, Ichiro Saito
      Pages 185-188
    5. Zhiyan Huang, Ross W. Lambert, L. Alexandra Wickham, David A. Sullivan
      Pages 189-192
    6. L. Alexandra Wickham, Zhiyan Huang, Ross W. Lambert, David A. Sullivan
      Pages 193-196
  7. Molecular Biological Approaches to the Study of the Lacrimal Gland and Tear Film

    1. Hilary W. Thompson, Roger W. Beuerman, Julie Cook, Lauren W. Underwood, Doan H. Nguyen
      Pages 211-217
    2. Jianping Gao, Ross W. Lambert, L. Alexandra Wickham, David A. Sullivan
      Pages 219-224
    3. Michele M. Cripps, Hilary W. Thompson, Roger W. Beuerman
      Pages 225-230
  8. Tear Film Composition and Biophysical Properties

About this book


During the past decade a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays an essential role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in countless individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentially, pronounced visual disability and blindness. 7 To promote further progress in this field of vision research, the International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance was held in the Southampton Princess Resort in Bermuda from November 14 to 17, 1992. This meeting was designed to assess critically the current knowledge and 'state of the art' research on the structure and function of lacrimal tissue and tears in both health and disease. The goal of this conference was to provide an international exchange of information that would be of value to basic scientists involved in eye research, to physicians in the ophthalmological community, and to pharmaceutical companies with an interest in the treatment of lacrimal gland, tear film or ocular surface disorders (e. g. Sjogren's syndrome).


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Editors and affiliations

  • David A. Sullivan
    • 1
  1. 1.Schepens Eye Research Institute and Harvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Plenum Press, New York 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-6025-4
  • Online ISBN 978-1-4615-2417-5
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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