Intercellular Signalling in the Mammary Gland

1. Mammary Development: Growth and Growth Factors

   1. Endocrine Effect of IGF-I on Mammary Growth in Prepubertal Heifers

      • Stig Purup, Yael Sandowski, Kris Sejrsen

      Pages 93-94

   2. Local Control of Mammary Apoptosis by Milk Stasis

      • Lynda H. Quarrie, Caroline V. P. Addey, Colin J. Wilde

      Pages 95-96

   3. Immunolocalisation of Insulin-Like Growth Factors and Basic Fibroblast Growth Factor in the Bovine Mammary Gland

      • Dieter Schams, Werner Amselgruber, Fred Sinowatz

      Pages 97-98

   4. Flow Sorting and Clonal Analysis of Mouse Mammary Epithelium

      • Matthew Smalley, Jenny Titley, Michael J. O’Hare

      Pages 99-100

   5. Cytokine Expression in Normal and Neoplastic Breast Tissue

      • Valerie Speirs, Andrew R. Green, Victoria L. Todd, Michael C. White

      Pages 101-102

   6. Production of an Insulin-Like Growth Factor Binding Protein by the Involuting Rat Mammary Gland

      • Elizabeth Tonner, James Beattie, David J. Flint

      Pages 103-104

   7. Developmental and Hormonal Regulation of Wnt Gene Expression in the Mouse Mammary Gland

      • Stephen Weber-Hall, Deborah Phippard, Christina Niemeyer, Trevor Dale

      Pages 105-106

2. Mammary Development: Differentiation and Gene Expression

   1. Extracellular Matrix Dependent Gene Regulation in Mammary Epithelial Cells

      • Christian Schmidhauser, Connie A. Myers, Romina Mossi, Gerald F. Casperson, Mina J. Bissell

      Pages 107-119

   2. α-Lactalbumin Regulation and Its Role in Lactation

      • Robert D. Bremel

      Pages 121-129

   3. Regulation of Milk Secretion and Composition by Growth Hormone and Prolactin

      • David J. Flint

      Pages 131-140

   4. Basement Membrane in the Control of Mammary Gland Function

      • Charles H. Streuli

      Pages 141-151

   5. Asynchronous Concurrent Secretion of Milk Proteins in the Tammar Wallaby (Macropus Eugenii)

      • Kevin R. Nicholas, Colin J. Wilde, Peter H. Bird, Kay A. K. Hendry, Karen Tregenza, Beverley Warner

      Pages 153-170

   6. Heterogeneous Expression and Synthesis of Human Serum Albumin in the Mammary Gland of Transgenic Mice

      • Itamar Barash, Alexander Faerman, Raisa Puzis, Margaret Natan, David R. Hurwitz, Moshe Shani

      Pages 171-172

   7. Post-Transcriptional Regulation of Casein Gene Expression by Prolactin and Growth Hormone in Lactating Rat Mammary Gland

      • Michael C. Barber, Amanda J. Vallance, David J. Flint, Richard G. Vernon, Maureen T. Travers

      Pages 173-174

   8. Characterization of Transcriptional Control Elements in the Mammary Gland and Pancreas: Studies of the Carboxyl Ester Lipase Gene

      • Ulf Lidberg, Jeanette Nilsson, Gunnar Bjursell

      Pages 175-176

   9. Oligosaccharide Analysis of Epithelial Mammary Tissues

      • Anthony J. C. Leathem, Susan A. Brooks, Miriam V. Dwek, Udo Schumacher

      Pages 177-178

   10. Human Bile Salt-Activated Lipase: Structural Organisation at the C-Terminus

       • Kerry M. Loomes

       Pages 179-180

   11. Dramatic Changes in Gap Junction Expression in the Mammary Gland During Pregnancy, Lactation and Involution

       • Paul Monaghan, Nina Perusinghe, W. Howard Evans

       Pages 181-182

   12. Aromatase Induction in Stromal Vascular Cells from Human Breast Adipose Tissue by Growth Factors

       • Martin Schmidt, Georg Löffler

       Pages 183-184

   13. Developmental Regulation of Homeobox Genes in the Mouse Mammary Gland

       • Deborah Phippard, Paul Sharpe, Trevor Dale

       Pages 185-186

All being done, we went to Mrs Shipmans, who is a great butter-woman; and I did see there the most of milke and cream, and the cleanest, that I ever saw in my life (29 May 1661). Among others, Sir Wm. Petty did tell me that in good earnest, he hath in his will left such parts of his estate to him that could invent such and such things -as among others, that could discover truly the way of milk coming into the breasts of a woman ... (22 March 1665). My wife tells me that she hears that my poor aunt James hath had her breast cut off here in tow- her breast having long been out of order (5 May 1665). From the Diary of Samuel Pepys, published as The Shorter Pepys (edited by R. Latham), Penguin Books (1987) The long-standing ultimate importance of research on the mammary gland is illustrated by the importance attached to cows' milk for human consumption, to human lactation and to breast cancer by Samuel Pepys and his contemporaries in the middle of the 17th century. Research has tended to develop in isolation in these three areas of continuing contemporary importance largely because in most countries, the underlying science of agricultural productivity is funded separately from the underlying science of human health and welfare.

• development
• gene expression
• genes
• growth
• placenta

• Hannah Research Institute, Ayr, Scotland, UK

  Colin J. Wilde, Malcolm Peaker, Christopher H. Knight

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