© 1995

Dendritic Cells in Fundamental and Clinical Immunology

Volume 2

  • Jacques Banchereau
  • Daniel Schmitt

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 378)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Dendritic Cells: Origin and Differentiation

    1. C. Caux, B. Vanbervliet, C. Massacrier, B. Dubois, C. Dezutter-Dambuyant, D. Schmitt et al.
      Pages 1-5
    2. Frances Santiago-Schwarz, Karen Laky, Steven E. Carsons
      Pages 7-11
    3. Ken Shortman, Li Wu, Carlos Ardavin, David Vremec, Frank Sotzik, Ken Winkel et al.
      Pages 21-29
    4. F. Granucci, G. Girolomoni, M. B. Lutz, P. Ricciardi-Castagnoli
      Pages 31-34
    5. Geoffrey Rowden, Shirley Dean, Pat Colp
      Pages 39-41
    6. Gerold Schuler, Daniela Brang, Nikolaus Romani
      Pages 43-52
    7. Melissa Chen-Woan, Conor P. Delaney, Veronique Fournier, Yoshitaka Wakizaka, Noriko Murase, Angus W. Thomson et al.
      Pages 53-55
    8. Frans G. A. Delemarre, Petra Mooij, Meeny de Haan-Meulman, Peter J. Simons, Harm J. de Wit, Hemmo A. Drexhage
      Pages 57-59
    9. Hubertus Hochrein, Frank Jährling, H.-Georg Kreysch, Arne Sutter
      Pages 61-63
    10. Kayo Inaba, Muneo Inaba, Margit Witmer-Pack, Karen Hathcock, Richard Hodes, Ralph M. Steinman
      Pages 65-70
    11. M. Mehlig, C. Scheicher, H.-P. Dienes, K. Reske
      Pages 71-73
  3. Dendritic Cells: Phenotype

    1. J. Banchereau, B. Dubois, J. Fayette, N. Burdin, F. Brière, P. Miossec et al.
      Pages 79-83
    2. C. T. Tiemessen, S. Shalekoff, L. Morris, Y. Becker, D. J. Martin
      Pages 85-87
    3. Jean-Pierre Aubry, Christine Power, Paul Life, Magdalena Schrader, Jean-Yves Bonnefoy
      Pages 89-91

About this book


These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic cells and lymph dendritic cells (veiled cells). Although dendritic cells in each of these compartments are all CD45+ leukocytes that arise from the bone marrow, they may exhibit differences that relate to maturation state and microenvironment. Dendritic cells are specialized antigen-presenting cells for T lymphocytes: they process and present antigens efficiently in situ, and stimulate responses from naive and memory T cells in the paracortical area of secondary lymphoid organs. Recent evidence also demonstrates their role in induction of tolerance. By contrast, the primary and secondary B-cell follicles contain follicular dendritic cells that trap and retain intact antigen as immune complexes for long periods of time. The origin of follicular dendritic cells is not clear, but most investigators believe that these cells are not leukocytes.


Antigen blood bone marrow development lymphocytes migration phenotype tissue transplantation

Editors and affiliations

  • Jacques Banchereau
    • 1
  • Daniel Schmitt
    • 2
  1. 1.Laboratory for Immunological ResearchSchering-PloughDardillyFrance
  2. 2.INSERM U346Hôpital Edouard HerriotLyonFrance

Bibliographic information

  • Book Title Dendritic Cells in Fundamental and Clinical Immunology
  • Book Subtitle Volume 2
  • Editors Jacques Banchereau
    Daniel Schmitt
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Plenum Press, New York 1995
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-45078-5
  • Softcover ISBN 978-1-4613-5811-4
  • eBook ISBN 978-1-4615-1971-3
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XIX, 572
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Hematology
    Animal Anatomy / Morphology / Histology
    Plant Sciences
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