© 2001

Mechanisms of Lymphocyte Activation and Immune Regulation VIII

Autoimmunity 2000 and Beyond

  • Sudhir Gupta

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 490)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Basic Mechanisms

    1. Kristine M. Garza, Linh T. Nguyen, Russell G. Jones, Pamela S. Ohashi
      Pages 7-19
    2. Ethan M. Shevach, Rebecca S. McHugh, Angela M. Thornton, Ciriaco Piccirillo, Kannan Natarajan, David H. Margulies
      Pages 21-32
    3. Christopher C. Goodnow, Richard Glynne, Srini Akkaraju, Jane Rayner, David Mack, James I. Healy et al.
      Pages 33-40
    4. Harald von Boehmer, Elmar Jaeckel
      Pages 41-48
    5. Hyung J. Chun, Michael J. Lenardo
      Pages 49-57
  3. Pathogenesis

  4. Therapy

    1. Lawrence Steinman
      Pages 109-112
    2. David I. Daikh, David Wofsy
      Pages 113-117
    3. Marc Feldmann, Ravinder N. Maini, Jan Bondeson, Peter Taylor, Brian M. J. Foxwell, Fionula M. Brennan
      Pages 119-127
  5. Back Matter
    Pages 129-136

About this book


Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies.
This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.


T cell autoimmune disease autoimmunity biochemistry biology cell cell biology cytokine diseases gene expression immunosuppression pathogenesis virus

Editors and affiliations

  • Sudhir Gupta
    • 1
  1. 1.University of California, IrvineIrvineUSA

Bibliographic information

  • Book Title Mechanisms of Lymphocyte Activation and Immune Regulation VIII
  • Book Subtitle Autoimmunity 2000 and Beyond
  • Editors Sudhir Gupta
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 2001
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-46570-3
  • Softcover ISBN 978-1-4613-5458-1
  • eBook ISBN 978-1-4615-1243-1
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages VIII, 136
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Biochemistry, general
  • Buy this book on publisher's site
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