The Identities of Membrane Steroid Receptors

...And Other Proteins Mediating Nongenomic Steroid Action

  • Cheryl S. Watson

Table of contents

  1. Front Matter
    Pages i-xiv
  2. “Nuclear” Receptors in the Membrane

    1. Diana C. Márquez, Richard J. Pietras
      Pages 1-9
    2. Cheryl Watson, Dragoslava Zivadinovic, Nataliya Bulayeva, Bridget Hawkins, Celeste Campbell, Bahiru Gametchu
      Pages 11-19
    3. Teresa A. Milner, Stephen E. Alves, Shinji Hayashi, Bruce S. McEwen
      Pages 21-25
    4. Bahiru Gametchu, Cheryl S. Watson
      Pages 47-55
    5. Daniela Capiati, Graciela Santillán, Ana Rossi, Paula Monje, Ricardo Boland
      Pages 57-65
  3. Nuclear Receptors Physically Interact with Signal Cascade Molecules

    1. Ferdinando Auricchio, Antimo Migliaccio, Gabriella Castoria, Marina Di Domenico
      Pages 77-83
    2. Sigrun Mink, Liubov Shatkina, Andrea Nestl, Andrew C. B. Cato
      Pages 111-117
  4. Unique, Previously Undescribed Receptors

    1. Ralf Lösel, Michael Christ, Christoph Eisen, Elisabeth Falkenstein, Martin Feuring, Christiane Meyer et al.
      Pages 125-129
    2. Cheryl A. Frye, Sandra M. Petralia
      Pages 165-168
  5. Protens with Identites or Similarities to Other Non-Receptor Proteins

    1. Brian J. Harvey, Christina M. Doolan
      Pages 177-185
  6. Chimeras

  7. Receptorc for Serumbinding Proteins

    1. Scott M. Kahn, Daniel J. Hryb, Atif M. Nakhla, Nicholas A. Romas, William Rosner
      Pages 193-200
  8. Back Matter
    Pages 201-208

About this book


Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. Based on these and other considerations, an alternative membrane-associated receptor form was long ago proposed to exist (3). Others interpret the location of the steroid receptors mediating these rapid effects as peri­ membrane or cytoplasmic. New experimental tools have been brought to bear on the topic of receptors for steroids which mediate non-genomic actions, and thus investigative activity and focus regarding this type of steroid receptor has recently increased significantly. However, there may be multiple answers to the question "how do steroids mediate rapid nongenomic effects?" Steroid actions initiated at the cell membrane can impinge on important phases in the lifespan of a cell: proliferation, migration, differentiation, and release of hormones or neurotransmitters functioning as signals to other cells.


G proteins Vitamin D enzymes estrogen receptor nuclear receptors proteins regulation signal transduction transcription

Editors and affiliations

  • Cheryl S. Watson
    • 1
  1. 1.University of Texas Medical BranchUSA

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