Leptin and Reproduction

  • Michael C. Henson
  • V. Daniel Castracane

Table of contents

  1. Front Matter
    Pages i-xx
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Michael C. Henson, V. Daniel Castracane, Deborah E. Edwards
      Pages 3-11
  3. General Reproductive Function

    1. Front Matter
      Pages 13-13
    2. S. M. McCann, S. Karanth, W. H. Yu, C. A. Mastronardi
      Pages 15-37
    3. Robert V. Considine
      Pages 39-51
    4. Ioannis E. Messinis, Ekaterini Domali
      Pages 53-76
    5. John D. Brannian, Keith A. Hansen
      Pages 77-95
    6. Joaquin Lado-Abeal, Reid L. Norman
      Pages 117-129
  4. Puberty

    1. Front Matter
      Pages 131-131
    2. David R. Mann, Tony M. Plant
      Pages 133-150
    3. Susann Blüher, Christos S. Mantzoros
      Pages 151-167
    4. Douglas L. Foster, Leslie M. Jackson
      Pages 169-186
  5. Pregnancy

    1. Front Matter
      Pages 187-187
    2. Helen Christou, Shanti Serdy, Christos S. Mantzoros
      Pages 189-200
    3. Dorina Islami, Paul Bischof
      Pages 201-220
    4. Brendan J. Waddell, Jeremy T. Smith
      Pages 221-237
    5. Michael C. Henson, V. Daniel Castracane
      Pages 239-263
  6. Genetics

    1. Front Matter
      Pages 265-265
    2. Farid F. Chehab, Amanda Ewart-Toland, Khalid Mounzih, Jun Qiu, Scott Ogus
      Pages 267-286
    3. I. Sadaf Farooqi
      Pages 287-295
  7. Clinical Challenges

    1. Front Matter
      Pages 297-297
    2. Lucilla Poston
      Pages 299-310
    3. Michelle P. Warren, Jennifer E. Dominguez
      Pages 311-332
    4. Denis A. Magoffin, Priya S. Duggal, Robert J. Norman
      Pages 333-345
  8. Back Matter
    Pages 347-352

About this book


The isolation of leptin in 1994 and its characterization as a factor influencing appetite, energy balance, and adiposity, immediately thrust the polypeptide into the rapidly growing body of literature centered on the physiology of obesity. The growing clinical awareness of obesity as a major health risk in developed societies dovetailed perfectly with any of a number of roles that leptin might play in this abenant physiological condition. Almost unnoticed amidst the excitement generated by early leptin publications was the suggestion that the "fat hormone" might also regulate a wide range of systems and events important to reproduction, including pubertal development, gonadal endocrinology, fettility, and pregnancy. Recognizing this potential, a relatively small cadre of researchers began to examine leptin specifically as a reproductive hormone, thus creating a new and fertile field of investigation. Interest in this area has since gained momentum and an increased number of participants have now made significant contributions to our understanding of many leptin-related mechanisms that are relevant to reproductive biology. Leptin and Reproduction is the first major volume to specifically address leptin as a reproductive hormone and closely examines the advances made in the short time since this field of interest developed. Preeminent researchers ti'om many of the subdisciplines working within this area present a welcomed compendium of the wealth of related literature and voice novel interpretations of cun'ent advances.


biology development embryology genetics infertility physiology reproductive system

Editors and affiliations

  • Michael C. Henson
    • 1
  • V. Daniel Castracane
    • 2
    • 3
  1. 1.Tulane University Health Sciences CenterNew OrleansUSA
  2. 2.Texas Tech Health Sciences CenterAmarilloUSA
  3. 3.Diagnostic Systems Laboratories, Inc.WebsterUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 2003
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-4946-4
  • Online ISBN 978-1-4615-0157-2
  • Buy this book on publisher's site