© 2003

Retinal Degenerations

Mechanisms and Experimental Therapy

  • Matthew M. LaVail
  • Joe G. Hollyfield
  • Robert E. Anderson
Conference proceedings

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 533)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Stephen P. Daiger, Lori S. Sullivan, Sara J. Bowne, Avril Kennan, Peter Humphries, David G. Birch et al.
    Pages 1-11
  3. Avril Kennan, Aileen Aherne, Sara J. Bowne, Stephen P. Daiger, G. Jane Farrar, Paul F. Kenna et al.
    Pages 13-18
  4. Patsy M. Nishina, Jürgen K. Naggert
    Pages 29-34
  5. R.S. Ramesar, L. Roberts, G. Rebello, R. Goliath, A. Vorster, A. September et al.
    Pages 35-40
  6. Anthony G. Robson, Catherine Egan, Graham E. Holder, Alan C. Bird, Fred W. Fitzke
    Pages 41-47
  7. N. Lodha, C. A. Westall, M. Brent, M. Abdolell, E. Héon
    Pages 49-57
  8. Fernanda B. O. Porto, Isabelle Perrault, David Hicks, Jean-Michel Rozet, Noëlle Hanoteau, Sylvain Hanein et al.
    Pages 59-68
  9. Isabelle Perrault, Sylvie Gerber, Sylvain Hanein, Serge Picaud, Jean-Michel Rozet, Jean-Louis Dufier et al.
    Pages 69-77
  10. Joe G. Hollyfield, Robert G. Salomon, John W. Crabb
    Pages 83-89
  11. Kimberly A. Howes, Jeanne M. Frederick, Alexander Marks, Wolfgang Baehr
    Pages 91-96
  12. Jian Hua Qi, Quteba Ebrahem, Bela Anand-Apte
    Pages 97-105
  13. Concepcion Lillo, Junko Kitamoto, Xinran Liu, Elizabeth Quint, Karen P. Steel, David S. Williams
    Pages 143-150
  14. Tania Slatter, Sassan M. Azarian, Scott Tebbutt, Marion Maw, David S. Williams
    Pages 151-155

About these proceedings


The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration.
Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.


Diabetes Stress death epidemiology etiology eye macular degeneration neurons receptor retina retinoblastoma

Editors and affiliations

  • Matthew M. LaVail
    • 1
  • Joe G. Hollyfield
    • 2
  • Robert E. Anderson
    • 3
  1. 1.Beckman Vision CenterUniversity of CaliforniaSan FranciscoUSA
  2. 2.Cole Eye InstituteThe Cleveland Clinic FoundationClevelandUSA
  3. 3.Dean A. McGee Eye InstituteUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA

Bibliographic information

  • Book Title Retinal Degenerations
  • Book Subtitle Mechanisms and Experimental Therapy
  • Editors Matthew M. LaVail
    Joe G. Hollyfield
    Robert E. Anderson
  • Series Title Advances in Experimental Medicine and Biology
  • DOI
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 2003
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-306-47781-2
  • Softcover ISBN 978-1-4613-4909-9
  • eBook ISBN 978-1-4615-0067-4
  • Series ISSN 0065-2598
  • Edition Number 1
  • Number of Pages XVI, 467
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Ophthalmology
    Tree Biology
  • Buy this book on publisher's site
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