Computational Methods for Three-Dimensional Microscopy Reconstruction

  • Gabor T. Herman
  • Joachim Frank

Part of the Applied and Numerical Harmonic Analysis book series (ANHA)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Joachim Frank, Gabor T. Herman
    Pages 1-5
  3. C. O. S. Sorzano, R. Marabini, J. Vargas, J. Otón, J. Cuenca-Alba, A. Quintana et al.
    Pages 7-42
  4. Robert Langlois, Jordan T. Ash, Jesper Pallesen, Joachim Frank
    Pages 43-66
  5. Bingxin Shen, Bo Chen, Hstau Liao, Joachim Frank
    Pages 67-95
  6. Amedee des Georges, Yaser Hashem, Sarah N. Buss, Fabrice Jossinet, Qin Zhang, Hstau Y. Liao et al.
    Pages 97-132
  7. Younes Benkarroum, Paul Gottlieb, Al Katz, Stuart W. Rowland, Doris Bucher, Gabor T. Herman
    Pages 133-156
  8. J. Otón, C. O. S. Sorzano, F. J. Chichón, J. L. Carrascosa, J. M. Carazo, R. Marabini
    Pages 187-220
  9. Lucas M. Oliveira, T. Yung Kong, Gabor T. Herman
    Pages 221-255
  10. Back Matter
    Pages 257-264

About this book


Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ in detail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology.


Computational Methods for Three-Dimensional Microscopy Reconstruction will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in the area of 3D imaging and modeling.


classification computational methods inverse problems structural biology three-dimensional microscopy reconstruction

Editors and affiliations

  • Gabor T. Herman
    • 1
  • Joachim Frank
    • 2
  1. 1.Department of Computer ScienceThe Graduate Center City University of New YorkNew YorkUSA
  2. 2.Department of Biology, Biochemistry and Molecular BiophysicsColumbia UniversityNew YorkUSA

Bibliographic information