© 2013

Next Generation Sequencing in Cancer Research

Volume 1: Decoding the Cancer Genome

  • Wei Wu
  • Hani Choudhry

Table of contents

  1. Front Matter
    Pages i-xii
  2. Chee-Seng Ku, Yudi Pawitan, Mengchu Wu, Dimitrios H. Roukos, David N. Cooper
    Pages 1-30
  3. Hong Kiat Ng, Dimitrios H. Roukos, Barry Iacopetta, Chee-Seng Ku
    Pages 31-53
  4. Aarti N. Desai, Abhay Jere
    Pages 55-74
  5. Arvind K. Singla, Chandini Thirukkumaran, Rajiv Dixit, Wei Wu
    Pages 75-90
  6. Johannes Schödel, David R. Mole
    Pages 91-117
  7. Russell Bonneville, Kenneth Nephew, Victor X. Jin
    Pages 119-135
  8. HoJoon Lee, Billy T. Lau, Hanlee P. Ji
    Pages 137-163
  9. Han Chang, Donald G. Jackson, Paul S. Kayne, Petra B. Ross-Macdonald, Rolf-Peter Ryseck, Nathan O. Siemers
    Pages 165-182
  10. Thalia A. Farazi, Carl S. Leonhardt, Thomas Tuschl
    Pages 233-261
  11. ShanCheng Ren, Min Qu, Yinghao Sun
    Pages 263-286
  12. Toby M. Ward, Anna-Maria Jegg, Elizabeth Iorns
    Pages 287-299
  13. Ayshwarya Subramanian, Stanley Shackney, Russell Schwartz
    Pages 335-357
  14. Xiaoping Su, Gabriel G. Malouf, Francisco J. Esteva
    Pages 359-371
  15. Back Matter
    Pages 373-383

About this book


Next Generation Sequencing (NGS) technology has placed important
milestones in the life science and changed the direction
in biomedical science inclucing cancer. Scientists around the
world are attempting to find the root cause of cancer and they
are looking for more direct and effective means to cure cancer.
This journey to conquer cancer is more optimistic now with
the unfolding of the cancer genome. This book focuses on the
application of various NGS in the frontier cancer genome research.
The 18 chapters in this volume have been written by
scientists with many outstanding contributions in their area
and the join effort has created comprehensive insightful view
on (1) Overview of next generation sequencing technology in
cancer genome research (2) Genome regulation and targeted
sequencing in cancer (3) RNA transcriptome (coding and
non-coding) in cancer genome (4)The challenges of computational
biology for cancer genome study.

This book is a state-of-the-art reference to all scientific researchers
and onologists who are interested in the understanding
of the cancer initiatome at whole genome scale and to those
are keen to translate the ‘base pairs to bedside’ for better management
of cancer patients in the era of personalized medicine.


NGS cancer genome cancer genomics high throughput sequencing mRNA

Editors and affiliations

  • Wei Wu
    • 1
  • Hani Choudhry
    • 2
  1. 1.Dept. Pathology & Laboratory MedicineUniversity of CalgaryCalgaryCanada
  2. 2.The Wellcome Trust Centre for Human GeneUniversity of OxfordOxfordUnited Kingdom

Bibliographic information

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