© 2013

Human Gametes and Preimplantation Embryos

Assessment and Diagnosis

  • David K. Gardner
  • Denny Sakkas
  • Emre Seli
  • Dagan Wells

Table of contents

  1. Front Matter
    Pages i-xv
  2. Markus Montag, Thomas Schimming, Maria Köster
    Pages 9-16
  3. Laura Rienzi, Benedetta Iussig, Filippo Ubaldi
    Pages 17-30
  4. María Cruz, Manuel Muñoz, Marcos Meseguer
    Pages 45-53
  5. Elpida Fragouli, Joy Delhanty
    Pages 107-124
  6. Alan H. Handyside, Dagan Wells
    Pages 135-145
  7. Mark A. Baker, R. John Aitken
    Pages 193-203
  8. Mandy G. Katz-Jaffe, Susanna McReynolds
    Pages 205-210

About this book


In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates.

Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.


ART Artificial insemination Assisted reproduction Genomics IVF In vitro fertilization Infertility Metabolomics Proteomics

Editors and affiliations

  • David K. Gardner
    • 1
  • Denny Sakkas
    • 2
  • Emre Seli
    • 3
  • Dagan Wells
    • 4
  1. 1.University of MelbourneDepartment of ZoologyMelbourneAustralia
  2. 2.Boston IVFWalthamUSA
  3. 3.Yale School of MedicineDept. of Ob/Gyn & Reproductive SciencesNew HavenUSA
  4. 4.Obstetrics & Gynaecology, University of OxfordNuffield Department ofOxfordUnited Kingdom

Bibliographic information

  • Book Title Human Gametes and Preimplantation Embryos
  • Book Subtitle Assessment and Diagnosis
  • Editors David K. Gardner
    Denny Sakkas
    Emre Seli
    Dagan Wells
  • DOI
  • Copyright Information Springer Science+Business Media New York 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-4614-6650-5
  • Softcover ISBN 978-1-4939-4268-8
  • eBook ISBN 978-1-4614-6651-2
  • Edition Number 1
  • Number of Pages XV, 306
  • Number of Illustrations 16 b/w illustrations, 48 illustrations in colour
  • Topics Reproductive Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals