Gametogenesis, Early Embryo Development and Stem Cell Derivation

  • Tiziana A.L. Brevini
  • Georgia Pennarossa

Part of the SpringerBriefs in Stem Cells book series (BRIEFSSTEM)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Tiziana.A.L. Brevini, Georgia Pennarossa
    Pages 1-25
  3. Tiziana A. L. Brevini, Georgia Pennarossa
    Pages 27-42
  4. Tiziana A. L. Brevini, Georgia Pennarossa
    Pages 43-62
  5. Back Matter
    Pages 63-66

About this book


This Brief offers a concise, handy overview of the main concepts related to Embryology, revisited through the novel concepts that are applied daily in stem cell research and cell therapy oriented investigations. It is based on three main areas:  

-The process involved in female gamete differentiation and maturation. The main aspects related to cell biology will be covered and an overview of the epigenetic regulation of gametogenesis will be presented.  

-Early stages of embryo development with a careful analysis of the regulatory mechanisms driving cleavage, polarization and genome activation.

-Stem cell and gametogenesis.

The use of the oocyte as a possible source for the derivation of stem cell lines is discussed and depicted as a powerful tool to investigate oocyte potency and asymmetric imprinting. The potential biological  implications are evaluated and use of stem cells to derive oocytes is presented. 


embryo development gametogenesis oocytes reproductive medicine stem cells

Authors and affiliations

  • Tiziana A.L. Brevini
    • 1
  • Georgia Pennarossa
    • 2
  1. 1.Unistem, Laboratory of Biomedical EmbryologyUniversità degli Studi di MilanoMilanItaly
  2. 2.Laboratorio di embriologia biomedica, (VESPA)Universita' Degli Studi Di MilanoMilanItaly

Bibliographic information

  • DOI
  • Copyright Information The Author(s) 2013
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-4614-5531-8
  • Online ISBN 978-1-4614-5532-5
  • Series Print ISSN 2192-8118
  • Series Online ISSN 2192-8126
  • Buy this book on publisher's site
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